ArticleAntibiotics (Basel, Switzerland)2026
Dual Analytical Evaluation of Generic Intravenous Vancomycin HCl in Saudi Arabia Using Microbiological and HPLC-DAD Approaches.
Article in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
BACKGROUND/
objectivesVancomycin hydrochloride (HCl) for injection is a vital antibiotic for severe infections. Vancomycin is an indispensable first-line antibiotic for life-threatening infections like methicillin-resistant
methodsUsing both microbiological and chemical methodologies as recommended by the US Pharmacopeia (USP) guidelines.
resultsThe microbiological assay, utilizing the USP "Antibiotics-Microbial Assay" method using
conclusionsBoth methods confirmed the potency of the tested generics within USP limits. However, minor variations observed between microbiological and chemical results highlight the importance of employing complementary techniques for comprehensive quality assessment. These findings underscore the importance of robust regulatory frameworks and ongoing post-market surveillance to ensure the continued safety, efficacy, and availability of quality-assured generic antibiotics in the Saudi market.
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