Evidence map›Paper›PMID 42192682›Full record

ArticleAntibiotics (Basel, Switzerland)2026

Antibiotics for Prophylaxis of Infective Endocarditis in Pediatric Patients: Knowledge and Prescribing Practices Between Italian Dentists.

Martina Barone, Giovanni Bruno, Christian Bacci, Michele Basilicata, Patrizio Bollero, Raffaella Docimo, Antonio Gracco, Alberto De Stefani, Filippo Cavallari

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Martina BaroneDepartment of Neuroscience, School of Dentistry, University of Padova, 35128 Padova, Italy.
Giovanni BrunoDepartment of Neuroscience, School of Dentistry, University of Padova, 35128 Padova, Italy.ORCID 0000-0003-2900-7196
Christian BacciDepartment of Neuroscience, School of Dentistry, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-6956-6227
Michele BasilicataUOSD Special Care Dentistry, Department of Experimental Medicine and Surgery, University of Roma Tor Vergata, 00133 Rome, Italy.
Patrizio BolleroUOSD Special Care Dentistry, Department of Experimental Medicine and Surgery, University of Roma Tor Vergata, 00133 Rome, Italy.
Raffaella DocimoPediatric Dentistry, Department of Surgical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.
Antonio GraccoDepartment of Neuroscience, School of Dentistry, University of Padova, 35128 Padova, Italy.
Alberto De StefaniDepartment of Neuroscience, School of Dentistry, University of Padova, 35128 Padova, Italy.
Filippo CavallariDepartment of Neuroscience, School of Dentistry, University of Padova, 35128 Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn pediatric dental care, antibiotics are routinely prescribed for both therapeutic and preventive purposes. Their use is primarily indicated for the management of widespread dental or oral infections, in conjunction with appropriate clinical treatment. Additionally, antibiotics are administered to prevent infective endocarditis (IE) in patients identified as being at increased risk. The present study aimed to evaluate the knowledge and prescribing practices of Italian dentists regarding antibiotic use in pediatric patients through an anonymous online questionnaire.

methodsA specifically designed questionnaire was electronically distributed to a group of Italian dentists. The questionnaire included three sections: demographic data, general knowledge on antibiotic prescribing, and IE prophylaxis in pediatric dentistry. Data were analyzed using appropriate statistical methods.

resultsThe study included 242 Italian dentists. Only a limited number of statistically significant differences were observed between specialists in pediatric dentistry and general dentists or those with other specializations, as well as between practitioners who mainly treat pediatric patients and those who predominantly treat adults. Regarding antibiotic prophylaxis for IE, most respondents identified amoxicillin as the first-line antibiotic for pediatric patients without penicillin allergy, whereas nearly 30% indicated clindamycin for patients with penicillin allergy. The knowledge about the dosage of assumption of the antibiotic of choice and the timing of administration of the antibiotic prophylaxis were considered as not sufficient.

conclusionsImportant gaps remain in dentists' knowledge of current guidelines for IE prophylaxis, particularly regarding drug dosage and administration. Increased awareness of updated recommendations and potential adverse effects of alternative antibiotics, such as clindamycin, is needed.

Indexed as

antibiotic prophylaxisantibioticsinfective endocarditispediatric dentistry

Identifiers

PMID42192682
PMCPMC13203871

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.