Evidence map›Paper›PMID 42192667›Full record

ReviewAntibiotics (Basel, Switzerland)2026

Biliary Microbiota in Health and Disease: Clinical Implications in Lithiasis, Infection, and Antimicrobial Resistance.

Claudia Marinaccio, Marta Giovanetti, Benedetto Neri, Dario Biasutto, Andrea D'Amico, Annamaria Altomare, Francesco Branda, Laura Restaneo, Massimo Ciccozzi, Michele Cicala and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claudia MarinaccioGastroenterology and Endoscopy Unit, Campus Bio Medico University of Rome, 00128 Rome, Italy.
Marta GiovanettiDepartment of Sciences and Technology for Sustainable Development and One Health, Campus Bio Medico University of Rome, 00128 Rome, Italy.ORCID 0000-0002-5849-7326
Benedetto NeriTherapeutic GI Endoscopy Unit, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-0803-7903
Dario BiasuttoTherapeutic GI Endoscopy Unit, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.
Andrea D'AmicoGastroenterology and Endoscopy Unit, Campus Bio Medico University of Rome, 00128 Rome, Italy.
Annamaria AltomareGastroenterology and Endoscopy Unit, Campus Bio Medico University of Rome, 00128 Rome, Italy.
Francesco BrandaUnit of Medical Statistics and Molecular Epidemiology, Campus Bio Medico University of Rome, 00128 Rome, Italy.ORCID 0000-0002-9485-3877
Laura RestaneoResearch Unit of Gastroenterology, Department of Medicine and Surgery, Campus Bio Medico University of Rome, 00128 Rome, Italy.
Massimo CiccozziUnit of Medical Statistics and Molecular Epidemiology, Campus Bio Medico University of Rome, 00128 Rome, Italy.ORCID 0000-0003-3866-9239
Michele CicalaGastroenterology and Endoscopy Unit, Campus Bio Medico University of Rome, 00128 Rome, Italy.ORCID 0000-0002-5370-2642
Michele Pier Luca GuarinoGastroenterology and Endoscopy Unit, Campus Bio Medico University of Rome, 00128 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biliary tract, long considered a sterile environment, is now recognized to harbor a resident microbiota with important implications for health and disease. This review aims to summarize current knowledge on the composition and function of the biliary microbiota in physiological conditions, and its alterations in pathological states such as infection and lithiasis, with a particular focus on antimicrobial resistance. In healthy individuals, the biliary microbiota appears to be shaped by bile acids and gut-bile axis interactions, playing a role in local immune modulation. In disease, microbial dysbiosis contributes to conditions such as acute cholecystitis, cholangitis, and gallstone formation, with distinct microbial signatures linked to specific stone types. Common biliary pathogens, including

Indexed as

antimicrobial resistancebiliary microbiotadysbiosisgut–liver axis

Identifiers

PMID42192667
PMCPMC13203847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.