Evidence map›Paper›PMID 42192640›Full record

ArticleBMJ open2026

Feasibility and acceptability of ENhanced Reviews of PsychologIcal Changes (ENRICH) after stroke: protocol.

Andrea Kusec, Georgina Hobden, Alexandra Wright-Hughes, Nele Demeyere

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea KusecNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-0128-4677
Georgina HobdenDepartment of Experimental Psychology, University of Oxford, Oxford, UK.
Alexandra Wright-HughesClinical Trials Research Unit, University of Leeds, Leeds, UK.ORCID http://orcid.org/0000-0001-8839-6756
Nele DemeyereNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK nele.demeyere@psy.ox.ac.uk.ORCID http://orcid.org/0000-0003-0416-5147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionManaging mood, cognition and fatigue are top unmet needs reported by stroke survivors, which impact quality of life. There is currently no standardised UK care pathway to support post-stroke psychological outcomes. The ENhanced Reviews of PsychologIcal Changes (ENRICH) programme, an intervention co-designed with stroke survivors, carers and healthcare professionals, aims to fill this gap. Here, we describe the protocol for evaluating the feasibility and acceptability of ENRICH. METHODS AND ANALYSIS: ENRICH reviews comprise cognition, mood and fatigue assessment, personalised psychoeducation and tools to communicate results and discuss self-management strategies, delivered at 1, 3 and 6 months post-stroke. N=140 participants (N=80 patients who had a stroke, N=45 carers, N=15 healthcare professionals) will be recruited to a single-arm multicentre feasibility study.Patients who had a stroke and carers will complete demographics at baseline (T1) questionnaires of quality of life, mood and healthcare resource use at 6 months post-stroke (T2) and an optional interview on experiences of ENRICH. Process evaluation will include fidelity assessment via audio recordings. Descriptive statistics will be calculated for study outcomes.Key qualitative acceptability outcomes are sought on intervention delivery by clinicians, patients and carers.Key intervention delivery feasibility outcomes relate to training clinicians (including competency and fidelity delivering ENRICH), and review completion rates. Study feasibility outcomes will include site and participant recruitment and retention rates and completion of candidate primary outcome measures on quality of life. ETHICS AND DISSEMINATION: The ENRICH study was approved by a UK Research Ethics Committee (reference: 24/LO/0341). Consent procedures include a waiver of consent to the intervention itself due ENRICH's service-level design and written informed consent/consultee advice for participants providing research data. Results will be disseminated through peer-reviewed publications, conferences and lay summaries for study participants and healthcare professionals. Results will inform whether ENRICH is acceptable to delivering clinicians and receiving patients who had a stroke and carers, and provide key insights to inform a future randomised trial to determine effectiveness. TRIAL REGISTRATION NUMBER: ISRCTN16018388.

Indexed as

Quality of LifeStrokeAffectCaregiversFatigueFeasibility StudiesHumansPatient Acceptance of Health CareResearch DesignSurveys and QuestionnairesUnited KingdomClinical ProtocolsCognitionDepression & mood disordersFeasibility StudiesQUALITATIVE RESEARCHStroke

Identifiers

PMID42192640
PMCPMC13202136

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.