Evidence map›Paper›PMID 42192548›Full record

SynthesisAntimicrobial resistance and infection control2026

Infection prevention, control and antimicrobial stewardship measures in intensive in-patient rehabilitation setting: a systematic review.

Matteo Raponi, Rossella Mancini, Silvia Martinelli, Mario Cesare Nurchis, Giuseppe Santoli, Rosa Liperoti, Patrizia Laurenti, Gianfranco Damiani

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Antimicrobial resistance and infection control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matteo RaponiDepartment of Women, Child and Public Health Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168, Rome, Italy. matteo.raponi@policlinicogemelli.it.
Rossella ManciniDepartment of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168, Rome, Italy.
Silvia MartinelliDepartment of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168, Rome, Italy.
Mario Cesare NurchisDepartment of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168, Rome, Italy.
Giuseppe SantoliDepartment of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, 00168, Rome, Italy.
Rosa LiperotiDepartment of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, 00168, Rome, Italy.
Patrizia LaurentiDepartment of Women, Child and Public Health Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168, Rome, Italy.
Gianfranco DamianiDepartment of Women, Child and Public Health Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe necessity for targeted strategies to prevent and manage multidrug-resistant organism infections in intensive rehabilitation settings is driven by the heightened vulnerability of patients, exacerbated by the unique organizational and technical aspects of these environments. This study aimed to establish an interpretative framework of internationally validated interventions to enhance infection prevention in intensive rehabilitation facilities. MATERIALS AND

methodsA systematic review, conducted following PRISMA guidelines, categorized interventions into three key domains: Antimicrobial Stewardship, Behavioural Prevention, and Sanitation and Environmental Cleaning.

resultsThe 17 articles selected for review provide a comprehensive overview of interventions within the three domains. Antimicrobial Stewardship interventions demonstrated potential in reducing Clostridioides difficile colonization through decreased antimicrobial use. Behavioural Prevention interventions were associated with reduced multidrug-resistant organism colonization and infections. Sanitation and Environmental Cleaning interventions, including hand hygiene, correlated with a decreased incidence of Clostridioides difficile cases. DISCUSSION AND

conclusionsThis systematic review underscores the importance of implementing multi-component interventions, encompassing both pharmacological and non-pharmacological approaches, across this critical setting.

Indexed as

Antimicrobial StewardshipCross InfectionInfection ControlRehabilitation CentersAnti-Bacterial AgentsClostridioides difficileClostridium InfectionsDrug Resistance, Multiple, BacterialHumansSanitationAnti-Bacterial AgentsAntimicrobial stewardshipBehavioural preventionEnvironmental cleaningIntensive rehabilitationMultidrug-resistant organism infections

Identifiers

PMID42192548
PMCPMC13393686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.