ArticleInternational journal of retina and vitreous2026
Macular micro vascular changes following macular hole repair: optical coherence tomography angiography study.
Article in International journal of retina and vitreous, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo detect changes in the macular vascular profile after macular hole closure using modified classic internal limiting membrane (ILM) peeling and temporal ILM flap techniques and their correlation with the macular microstructure and visual function. PATIENTS AND
methodsProspective comparative study that included 50 eyes with primary full-thickness macular hole (FTMH). Group A (n = 25) was treated using the modified classic ILM peeling technique, whereas group B (n = 25) was treated using the temporal ILM flap technique. The main outcome measures were macular hole closure, macular vascular and structural repair, and visual recovery rates. We performed OCT and OCTA using spectral-domain OCT (SD-OCT). The chi-square test was used to compare qualitative data, and the independent t-test was used to compare quantitative data. Analysis of variance test (ANOVA) was used to compare paired groups, and Spearman's correlation coefficients were used to assess the correlations between quantitative parameters. P-value < 0.05.
resultsAnatomical closure was comparable between groups A (80%) and B (88%) (p = 0.44). Both groups showed significant improvement in BCVA (p < 0.001), with no intergroup differences. The reduction in the FAZ area in the DCP was significant in both groups (p < 0.001). Only Group A showed a significant reduction in the FAZ in the SCP (p < 0.001). Preoperative hole dimensions correlated negatively with baseline BCVA and positively with FAZ in the SCP. Central macular thickness was inversely correlated with FAZ in both plexuses postoperatively. The magnitude of change in the FAZ in the DCP correlated negatively with the BCVA in groups A and B (p = 0.034 and p = 0.043, respectively).
conclusionFree ILM peeling and temporal ILM flap techniques achieved comparable anatomical closure rates and sustained visual improvement. Preoperative hole dimensions are major determinants of structural remodeling and functional recovery, while OCTA reveals substantial microvascular rearrangement, especially within the DCP, which correlates with visual recovery. CLINICAL TRIAL NUMBER: Not applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.