Evidence map›Paper›PMID 42192368›Full record

ArticleBMC public health2026

Socioeconomic inequalities in maternal infections during pregnancy: administrative health data evidence from a large UK urban area with high levels of inequality.

Iain Hardie, Kenneth Okelo, Josiah King, Aja Murray, Emily Luedecke, Hildigunnur Anna Hall, Michael V Lombardo, Louise Marryat, Bonnie Auyeung

Abstract read
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Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Iain HardieDepartment of Psychology, SchoolofPhilosophy,PsychologyandLanguage Sciences, University of Edinburgh, Edinburgh, UK. i.hardie@ed.ac.uk.
Kenneth OkeloDepartment of Psychology, SchoolofPhilosophy,PsychologyandLanguage Sciences, University of Edinburgh, Edinburgh, UK.
Josiah KingDepartment of Psychology, SchoolofPhilosophy,PsychologyandLanguage Sciences, University of Edinburgh, Edinburgh, UK.
Aja MurrayDepartment of Psychology, SchoolofPhilosophy,PsychologyandLanguage Sciences, University of Edinburgh, Edinburgh, UK.
Emily LuedeckeDepartment of Psychology, SchoolofPhilosophy,PsychologyandLanguage Sciences, University of Edinburgh, Edinburgh, UK.
Hildigunnur Anna HallCentre for Health Security and Communicable Disease Control, Directoratefor Health, Reykjavik, Iceland.
Michael V LombardoLaboratory for Autism and Neurodevelopmental Disorders, Center for Neuroscience and Cognitive Systems, Istituto Itialiano Di Tecnologia, Rovereto, Italy.
Louise MarryatSchool of Health Sciences, University of Dundee, Dundee, UK.
Bonnie AuyeungDepartment of Psychology, SchoolofPhilosophy,PsychologyandLanguage Sciences, University of Edinburgh, Edinburgh, UK.

Funding

Baily Thomas Charitable Fund TRUST/VC/AC/SG/469207686Economic and Social Research Council ES/W001519/1European Union's Horizon 2020 research and innovation programme 813546
6 · The paper itself

Abstract

backgroundMaternal infections during pregnancy (also known as prenatal infections) have been linked to adverse outcomes such as low birthweight, preterm birth, stillbirth and child developmental concerns, all of which have known socioeconomic inequalities. However, there is currently a lack of research into potential links between socioeconomic factors and prevalence of prenatal infections.

methodsWe utilised linked administrative health data including all children born in a large UK urban area with high levels of inequality, i.e. the National Health Service (NHS) health board of Greater Glasgow & Clyde, Scotland, 2010-2015 (N = 92,094). Logistic regression models were used to examine associations between socioeconomic factors (i.e. area-based Scottish Index of Multiple Deprivation (SIMD) quintiles and household-based UK National Statistics Socioeconomic Classification (NS-SEC)), and odds of prenatal infections, measured as hospital-diagnosed prenatal infections and infection-related prescriptions, with and without controlling for covariates.

resultsArea-based deprivation was generally associated with greater odds of prenatal infections, particularly for infections diagnosed in hospital. For example, living in a 'most deprived' SIMD quintile area was associated increased odds of both hospital-diagnosed prenatal infections (odds ratio (OR): 1.77; 95% confidence interval (CI): 1.48, 2.11) and infection-related prescriptions during pregnancy (OR: 1.28; 95% CI: 1.21, 1.36), when compared to living in a 'least deprived' SIMD quintile area, after covariate adjustment. Meanwhile, lower NS-SEC was also generally associated with increased odds of hospital-diagnosed prenatal infections, but there was not a clear pattern in associations between NS-SEC and infection-related prescriptions.

conclusionsArea-based deprivation, and to a lesser extent, lower household NS-SEC, appear to be associated with increased odds of maternal infections (particularly hospital-diagnosed maternal infections) during pregnancy in NHS Greater Glasgow & Clyde, Scotland. Socioeconomic inequalities in the prevalence of prenatal infections may therefore be a potential contributing factor to wider inequalities.

Indexed as

Pregnancy Complications, InfectiousSocioeconomic Disparities in HealthUrban PopulationAdultFemaleHumansLow Socioeconomic StatusPregnancyScotlandSocioeconomic FactorsUnited KingdomYoung AdultChildhood developmentPrenatal infectionsSocioeconomic inequalities

Identifiers

PMID42192368
PMCPMC13390274

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