Evidence map›Paper›PMID 42192311›Full record

ArticleBMC gastroenterology2026

Prevalence of symptoms of anxiety and depression in postoperative patients with Crohn's disease: a comparative cross-sectional study.

Awni Abu Sneineh, Sara Haj Ali, Tarek Mazzawi, Mohammad Sami Mohtaseb, Rasha Ali, Noor Abu Farsakh, Fares Senan, Sawsan Hodali, Lana Agraib, Osama Khatib and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Awni Abu SneinehGastroenterology Department, Faculty of Medicine, University of Jordan, Amman, 11942, Jordan.
Sara Haj AliInternal Medicine Department, Faculty of Medicine, Al-Balqa Applied University, Salt, 19117, Jordan. sara.hajali@bau.edu.jo.
Tarek MazzawiInternal Medicine Department, Faculty of Medicine, Al-Balqa Applied University, Salt, 19117, Jordan.
Mohammad Sami MohtasebGeneral Surgery Department, Faculty of Medicine, University of Jordan, Amman, 11942, Jordan.
Rasha AliGastroenterology Department, Faculty of Medicine, University of Jordan, Amman, 11942, Jordan.
Noor Abu FarsakhGastroenterology Department, Faculty of Medicine, University of Jordan, Amman, 11942, Jordan.
Fares SenanGastroenterology Department, Faculty of Medicine, University of Jordan, Amman, 11942, Jordan.
Sawsan HodaliGastroenterology Department, Faculty of Medicine, University of Jordan, Amman, 11942, Jordan.
Lana AgraibDepartment of Nutrition and Food Sciences, Faculty of Allied Medical Sciences, Al-Balqa Applied University, Salt, 19117, Jordan.
Osama KhatibGastroenterology Department, Faculty of Medicine, University of Jordan, Amman, 11942, Jordan.
Lana KhatibGastroenterology Department, Faculty of Medicine, University of Jordan, Amman, 11942, Jordan.
Ibrahim SablabanThe Oakland University William Beaumont school of Medicine, Rochester, MI, 48309, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsCrohn's disease is a chronic inflammatory condition often requiring surgical intervention, which can significantly impact a patient's quality of life and mental health. This study aimed to evaluate the prevalence of anxiety and depressive symptoms in surgically treated patients with Crohn's disease.

methodsA comparative cross-sectional study at a tertiary center included surgically and non-surgically treated patients with Crohn's disease. Anxiety and depressive symptoms were assessed using the Generalized Anxiety Disorder-7 questionnaire and Patient Health Questionnaire-9. Disease activity was assessed using Harvey Bradshaw index and endoscopic recurrence was evaluated using the Rutgeerts score.

resultsA total of 97 patients with Crohn's disease (54 surgical, 43 non-surgical controls) were included. The prevalence of anxiety and depressive symptoms were comparable between groups (57.4% surgical vs. 60.5% controls, p = 0.330) and (70.4% vs. 79.1%, p = 0.761), respectively. Surgical group had significantly better depression severity outcomes, with lower median Patient Health Questionnaire-9 scores (6.0 vs. 9.0, p = 0.007) and no cases of severe depression (0% vs. 14%, p = 0.025). Active disease was significantly associated with anxiety and depressive symptoms, whereas a lower body mass index was significantly associated with symptoms of depression.

conclusionPrevious surgery was not associated with lower prevalence of symptoms of anxiety or depression but was associated with significantly milder depression severity. The strong association of active disease and anxiety symptoms, and of active disease and lower body mass index with depressive symptoms, highlights the need for comprehensive care models that target both physical and psychological symptoms.

Indexed as

AnxietyCrohn DiseaseDepressionPostoperative ComplicationsAdultCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceQuality of LifeSeverity of Illness IndexSurveys and QuestionnairesYoung AdultAnxietyCrohn’s diseaseDepressionPostoperative careSurgery

Identifiers

PMID42192311
PMCPMC13390447

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.