ArticlePest management science2026
A bitter receptor links chemical detection to adaptive foraging avoidance in fire ants.
Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundBitter taste perception is critical for insect foraging decisions, yet the molecular basis of bitter-mediated deterrence remains poorly understood in invasive ants such as Solenopsis invicta. Elucidation of gustatory receptor mechanisms may facilitate the development of behaviorally informed strategies to modulate fire ant foraging.
resultsThe gustatory receptor SinvGr145 was broadly expressed in forager tissues and enriched in the antennae. Heterologous expression in HEK293T cells showed that the bitter compounds umbelliferone and L-canavanine selectively and dose-dependently activated SinvGr145, with EC
conclusionThis study identifies SinvGr145 as a molecular link between bitter chemical cues and deterrent foraging behavior in S. invicta. Targeting gustatory receptor-mediated bitter perception may provide a foundation for developing receptor-based strategies to regulate fire ant foraging in pest management programs. © 2026 Society of Chemical Industry.
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