Evidence map›Paper›PMID 42191648›Full record

ReviewThe British journal of radiology2026

Advanced quantitative CT for coronary artery disease: integrating stenosis quantification, plaque quantification, and fractional flow reserve-CT.

Samuel Mihalcioiu, Bethlehem Mengesha, Chen Abitbol, Fionn Coughlan, Jonathon Leipsic, Alexander Haenel

Abstract readReview
In one paragraph

Review in The British journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samuel MihalcioiuDepartment of Radiology, St. Paul's Hospital & University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.ORCID 0009-0003-1614-4607
Bethlehem MengeshaDepartment of Radiology, St. Paul's Hospital & University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.ORCID 0000-0002-9807-2816
Chen AbitbolDepartment of Radiology, St. Paul's Hospital & University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.
Fionn CoughlanDepartment of Medical Imaging, Fiona Stanley Hospital, Murdoch, WA, 6150, Australia.ORCID 0000-0001-5070-5330
Jonathon LeipsicDepartment of Radiology, St. Paul's Hospital & University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.ORCID 0009-0002-3892-9029
Alexander HaenelDepartment of Radiology, St. Paul's Hospital & University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.ORCID 0000-0002-5672-0547

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease (CAD) continues to be a leading cause of death globally. Radiological evaluation of CAD generally consists of stenosis detection by cardiac CT angiography (CCTA). However, this approach can be inefficient and subject to interobserver variability. In this review, we explore the newest developments related to CAD evaluation by CCTA, with an emphasis on plaque quantification. Artificial intelligence-based quantitative CT offers an efficient and reproducible method to analyze plaque biomarkers that support more refined risk stratification for major adverse cardiovascular events. Artificial intelligence-based coronary stenosis quantification can streamline workflow and improve consistency. The utilization of a photon-counting detector CT has been demonstrated to enhance spatial resolution, thereby allowing more precise coronary lumen analysis and artifact reduction. Fractional flow reserve-CT delivers a noninvasive physiologic assessment of stenotic lesions. Finally, we discuss the impact of these changes on risk stratification and guiding preventive therapy as well as possible future directions in this rapidly evolving field.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseCoronary StenosisFractional Flow Reserve, MyocardialPlaque, AtheroscleroticTomography, X-Ray ComputedArtificial IntelligenceHumans

Identifiers

PMID42191648
PMCPMC13623225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.