ArticleJournal of Korean medical science2026
Pregnancy Outcomes in Women With Valvular Heart Disease: Insights From 30 Years of Single-Center Experience.
Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundValvular heart disease (VHD) during pregnancy is associated with significant maternal and neonatal risks. While large-scale cohort studies have documented these risks in western populations, evidence in Korean women remains limited. This study aimed to evaluate maternal and neonatal outcomes by VHD severity and identify predictors of adverse events to inform risk assessment.
methodsThis retrospective study included 138 pregnant women with VHD who delivered at Samsung Medical Center between December 1994 and June 2023. Patients were stratified by VHD severity. The primary outcomes were adverse maternal outcomes, defined as maternal death or pregnancy-related complications requiring hospitalization, and adverse neonatal events, defined as neonatal intensive care unit admission or fetal death.
resultsMitral regurgitation was the most common lesion (47.8%). The incidence of adverse maternal outcomes increased with VHD severity (
conclusionVHD severity was associated with maternal heart failure hospitalization, but functional status and prior decompensation were equally important. These findings highlight the importance of pre-pregnancy evaluation and structured perinatal care. Multidisciplinary management may reduce complications, even in high-risk patients.
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