Evidence map›Paper›PMID 42190229›Full record

ReviewDermatology practical & conceptual2026

Dermatological Indicators of Systemic Autoimmune Disease: Clinical Links to Ocular Involvement.

Hana Abbas, Zarin Kothari, Harleen Multani, Kiratpreet Sraa, Precious Ochuwa Imokhai, Azka Malik, Sanjana Kantipudi, Danny Lee

Abstract readReview
In one paragraph

Review in Dermatology practical & conceptual, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hana AbbasMeharry Medical College School of Medicine, Nashville, TennesseeUSA.
Zarin KothariWayne State University School of Medicine, Detroit, MichiganUSA.
Harleen MultaniMeharry Medical College School of Medicine, Nashville, TennesseeUSA.
Kiratpreet SraaArizona College of Osteopathic Medicine, Glendale, ArizonaUSA.
Precious Ochuwa ImokhaiRocky Vista University, Montana College Of Osteopathic Medicine, Billings, MontanaUSA.
Azka MalikRoyal College of Surgeons in Ireland-Bahrain, Busaiteen, MuharraqBahrain.
Sanjana KantipudiVirginia Tech Carilion School of Medicine, Roanoke, VirginiaUSA.
Danny LeeDepartment of Medicine, University of California San Francisco St. Mary's Hospital, San Francisco, CaliforniaUSA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSystemic autoimmune diseases frequently involve both the skin and eyes, with early cutaneous manifestations often serving as visible indicators of deeper, multisystem pathology. Conditions such as systemic lupus erythematosus, dermatomyositis, sarcoidosis, and Sjögren's syndrome display characteristic skin findings, including malar rash, heliotrope eruption, lupus pernio, or xerosis, which may precede or parallel serious ocular complications, including uveitis, retinal vasculitis, conjunctival granulomas, and keratoconjunctivitis sicca. Despite this overlap, diagnostic and therapeutic strategies remain fragmented across specialties.

objectivesBy highlighting the clinical intersections between dermatological and ocular manifestations in systemic autoimmune diseases, we aim to promote earlier recognition, integrated treatment, and improved outcomes for patients affected by these multisystem disorders.

methodsThis review synthesizes the literature from the last fifteen years, between 2010 and 2025, on four major autoimmune conditions: systemic lupus erythematosus, dermatomyositis, sarcoidosis, and Sjögren's syndrome.

resultsWe examine disease-specific immunopathology, diagnostic modalities, and therapeutic strategies, while also discussing the need for interdisciplinary management models, including those that bridge dermatology and ophthalmology.

conclusionBy highlighting these clinical intersections, we aim to promote earlier recognition, integrated treatment, and improved outcomes for patients affected by these multisystem disorders.

Identifiers

PMID42190229
PMCPMC13211922

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.