Evidence map›Paper›PMID 42189996›Full record

ReviewProceedings of the National Academy of Sciences of the United States of America2026

Polyploidy: A macromutational force pushing bioeconomic developments.

Marlies K R Peeters, Yves Van de Peer

Abstract readReview
In one paragraph

Review in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Polyploidy and stress.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marlies K R PeetersDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0003-0737-6337
Yves Van de PeerDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0003-4327-3730

Funding

EC | Horizon Europe | Excellent Science | HORIZON EUROPE European Research Council (ERC) 833522UGent | Bijzonder Onderzoeksfonds UGent (BOF) Methusalem funding BOF.MET.2021.0005.01
6 · The paper itself

Abstract

Polyploidization, the consequence of genome doubling, is a macromutation that reshapes genomes, phenotypes, and ecological interactions. Polyploidization often results in novel phenotypes, including alterations in size, physiology, biochemistry, and enhanced stress tolerance. Here, we discuss how strategically leveraging polyploidy can provide significant advancements within the modern bioeconomy committed to reducing our ecological footprint through the sustainable production and use of biological resources. The bioeconomy spans diverse sectors, including agriculture, health sciences, and biotechnology. By elucidating and leveraging the immediate, or short-term, effects of polyploidization, such as harnessing genetic diversity, extensive biomass production, diversification of metabolites, and improved stress resilience, we highlight how this process unlocks vast, underexplored bioeconomic opportunities. This includes accelerating the exploration of new breeding techniques, speeding up the domestication of new local varieties or medicinal plants, and offering possibilities for improved biofuel production, bioremediation strategies, therapies, and production and discovery of bioactive compounds. The multilayered effects of polyploidization shared across sectors can foster interdisciplinary exchange and are essential for advancing toward a more sustainable bioeconomy.

Indexed as

BiotechnologyPolyploidyAgricultureBiofuelsBiomassBiofuelsadaptabilitybioeconomygenetic diversitymetabolic capacitymorphological changes

Identifiers

PMID42189996
PMCPMC13229275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.