Evidence map›Paper›PMID 42189884›Full record

ArticlePLoS neglected tropical diseases2026

Expanded molecular evidence of soil-transmitted helminth and Schistosoma spp. infections in Myanmar schoolchildren: A qPCR update.

Eindra Aung, Natasha Collinson, Kay Thwe Han, Nyein Nyein Hlaing, Moe Moe Aye, Myo Win Htun, Khin Thet Wai, Su Mon Myat, Thida Lay Thwe, Aung Tun and 8 more

Abstract read
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In one paragraph

Article in PLoS neglected tropical diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Eindra AungSchool of Clinical Medicine, University of New South Wales, Sydney, Australia.
Natasha CollinsonQIMR Berghofer, Infection and Inflammation, Applied Tropical and Molecular Parasitology, Brisbane, Australia.
Kay Thwe HanParasitology Research Division, Department of Medical Research, Ministry of Health and Sports, ‌‌Yangon, Myanmar.
Nyein Nyein HlaingDepartment of Zoology, University of Yangon, Yangon, Myanmar.
Moe Moe AyeDepartment of Zoology, Maubin University, ‌‌Maubin, Myanmar.
Myo Win HtunParasitology Research Division, Department of Medical Research, Ministry of Health and Sports, ‌‌Yangon, Myanmar.
Khin Thet WaiParasitology Research Division, Department of Medical Research, Ministry of Health and Sports, ‌‌Yangon, Myanmar.
Su Mon MyatDepartment of Public Health, Ministry of Health and Sports, Nay Pyi Taw, Myanmar.
Thida Lay ThweDepartment of Zoology, Yangon University of Distance Education, Yangon, Myanmar.
Aung TunMinistry of Health and Sports, Nay Pyi Taw, Myanmar.
Kinley WangdiHEAL Global Research Centre, Health Research Institute, Faculty of Health, University of Canberra, Canberra, Australia.
Yuesheng LiHunan Institute of Parasitic Diseases, World Health Organization Collaborating Centre for Research and Control on Schistosomiasis in Lake Region, Yueyang, China.
Gail M WilliamsSchool of Public Health, University of Queensland, Brisbane, Australia.
Archie C A ClementsQueen's University Belfast, Belfast, Northern Ireland, United Kingdom.
Susana Vaz NeryThe Kirby Institute, University of New South Wales, Sydney, Australia.
Donald P McManusQIMR Berghofer, Infection and Inflammation, Applied Tropical and Molecular Parasitology, Brisbane, Australia.
Darren J GrayQIMR Berghofer, Population Health, Global Health and Tropical Medicine, Brisbane, Australia.
Catherine A GordonQIMR Berghofer, Infection and Inflammation, Applied Tropical and Molecular Parasitology, Brisbane, Australia.ORCID https://orcid.org/0000-0002-1509-5220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Building on our previous report of high prevalence of soil-transmitted helminth (STH) infections among Myanmar schoolchildren (Aung et al., Infectious Diseases of Poverty, 2022), we conducted additional molecular screening of archival stool samples from the same cohort in Phyu Township, Bago Region, to investigate additional helminth infections. We also report finding of other helminths by Kato-Katz in the previous study that were not previously published. Stool samples utilised in this study were collected in 2016 and the DNA extracted in 2017 and kept stored at -20°C until further molecular characterisation in this study in 2025. Using quantitative PCR (qPCR), we detected Schistosoma DNA in two of 264 samples, Strongyloides stercoralis DNA in twelve, and Ancylostoma ceylanicum in eleven. Although sequencing of the Schistosoma-positive samples was unsuccessful, the molecular evidence aligns with other recent reports suggesting emerging or cryptic transmission of schistosomiasis in Myanmar. The epidemiology of schistosomiasis in the region remains poorly defined, highlighting the need for targeted snail surveys, environmental DNA (eDNA) monitoring, and host sampling to confirm transmission foci. This study demonstrates the added value of molecular diagnostics for complementing traditional parasitological methods and guiding surveillance and control strategies in areas of emerging endemicity.

Indexed as

HelminthiasisHelminthsSchistosomaSchistosomiasisSoilAdolescentAncylostomaAnimalsChildDNA, HelminthFecesFemaleHumansMaleMyanmarPrevalenceDNA, HelminthSoil

Identifiers

PMID42189884
PMCPMC13235887

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.