ArticlePloS one2026
Knowledge gaps and structural barriers to prescribing pre-exposure prophylaxis among healthcare providers in North Louisiana: A cross-sectional study.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPre-exposure prophylaxis (PrEP) uptake remains low in the Southern United States, despite disproportionate HIV burden. This study aimed to assess knowledge, attitudes, and structural barriers influencing PrEP prescribing among healthcare providers in North Louisiana.
methodsWe conducted a cross-sectional survey from January 2024 to April 2025 among 102 healthcare providers at a medical school and an affiliated hospital in North Louisiana. The survey assessed knowledge of PrEP, prescribing practices, and the perceived barriers. Descriptive statistics and multivariable logistic regression analysis were performed.
resultsAmong 102 healthcare providers, only 27.5% had ever prescribed PrEP, and 48% had never discussed it with patients. The most frequently reported barriers to prescribing PrEP were lack of provider training (84.3%) and absence of clinical guidelines (68.6%). Multivariable analyses showed that providers with higher self-rated PrEP knowledge were significantly more likely to discuss PrEP with patients (adjusted odds ratio [aOR]: 5.10; 95% confidence interval [CI]: 2.31-11.27) and to prescribe PrEP (aOR: 3.29; 95% CI: 1.72-6.30).
conclusionSignificant gaps in provider knowledge and institutional readiness persist in high-burden Southern settings. Targeted provider training and supportive institutional policies are essential to improving PrEP implementation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.