Evidence map›Paper›PMID 42189714›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Rapid Fragment Screening by

Laura Ruduša, Sintija Ozola, Kostiantyn P Melnykov, Yaroslav I Filatov, Serhiy V Ryabukhin, Raitis Bobrovs, Dmytro M Volochnyuk, Kristaps Jaudzems, Rihards Aleksis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura RudušaLatvian Institute of Organic Synthesis, Riga, Latvia.
Sintija OzolaLatvian Institute of Organic Synthesis, Riga, Latvia.
Kostiantyn P MelnykovEnamine Ltd, Kyiv, Ukraine.
Yaroslav I FilatovEnamine Ltd, Kyiv, Ukraine.
Serhiy V RyabukhinEnamine Ltd, Kyiv, Ukraine.
Raitis BobrovsLatvian Institute of Organic Synthesis, Riga, Latvia.
Dmytro M VolochnyukEnamine Ltd, Kyiv, Ukraine.
Kristaps JaudzemsLatvian Institute of Organic Synthesis, Riga, Latvia.
Rihards AleksisLatvian Institute of Organic Synthesis, Riga, Latvia.

Funding

Diamond Light Source mx39641Recovery and Resilience Facility fund 23/OSI/DGRecovery and Resilience Facility fund 64/OSI/PG
6 · The paper itself

Abstract

Steady-state free precession (SSFP) NMR is emerging as a powerful tool across multiple fields of magnetic resonance, driven by its high sensitivity and advances in acquisition and processing. By continuously detecting steady-state transverse magnetization, SSFP achieves superior signal-to-noise ratios per square-root unit time compared to conventional NMR methods that require magnetization recovery between scans. Here, we demonstrate the application of

Indexed as

drug discoveryfragment screeningSSFP

Identifiers

PMID42189714
PMCPMC13383281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.