Evidence map›Paper›PMID 42189458›Full record

ReviewAIDS and behavior2026

A Narrative Review of Remote Biospecimen Collection Product and Implementation Considerations for Sexual Health Clinical Research.

Keith J Horvath, Sarah E Rutstein, Ryan P Coyle, Cheryl Jennings, Rahim Z Miller, Justin Unternaher, Kelly Bojan, Grace M Aldrovandi, K Rivet Amico, Peter L Anderson and 4 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Keith J HorvathDepartment of Psychology, College of Sciences, San Diego State University, 5500 Campanile Drive, San Diego, CA, USA. khorvath@sdsu.edu.ORCID http://orcid.org/0000-0001-7569-2839
Sarah E RutsteinDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-1571-6576
Ryan P CoyleDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID http://orcid.org/0000-0001-6472-7020
Cheryl JenningsDepartment of Research Shared Services, Rush University Medical Center, Chicago, IL, USA.ORCID http://orcid.org/0009-0002-3508-5350
Rahim Z MillerInstitute on Digital Health and Innovation, College of Nursing, Florida State University, Tallahassee, FL, USA.ORCID http://orcid.org/0009-0006-6995-1543
Justin UnternaherDivision of Infectious Diseases, Children's National Hospital, Washington, DC, USA.ORCID http://orcid.org/0000-0003-1669-6455
Kelly BojanDepartment of Medicine, Center for Dissemination and Implementation Science, University of Illinois, Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-2967-7632
Grace M AldrovandiDepartment of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-1604-9637
K Rivet AmicoDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, USA.ORCID http://orcid.org/0000-0002-4458-6934
Peter L AndersonDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID http://orcid.org/0000-0002-1200-8494
Nadia DowshenDivision of Adolescent Medicine, Department of Pediatrics, Perelman School of Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-8466-1628
Sybil HosekDepartment of Medicine, Center for Dissemination and Implementation Science, University of Illinois, Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-5230-0759
Lisa Hightow-WeidmanInstitute on Digital Health and Innovation, College of Nursing, Florida State University, Tallahassee, FL, USA.ORCID http://orcid.org/0000-0002-2421-923X
Mark A MarzinkeDepartments of Pathology and Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-1670-8786

Funding

Statistical and Data Management Center-Pediatric,Adolescent, and Maternal CTGUM1AI068616 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Sean Scott Brummel, Marlene Ann Cooper · 2011 to 2026
$155.6M
LC - IMPAACT Leadership GroupUM1AI106716 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Grace M Aldrovandi · 2014 to 2026
$47.2M
Eunice Kennedy Shriver National Institute of Child Health and Human Development UM2HD111076Eunice Kennedy Shriver National Institute of Child Health and Human Development UM2HD111102NIAID NIH HHS UM1 AI068616NIAID NIH HHS UM1 AI106716
6 · The paper itself

Abstract

Remote biospecimen collection (RBSC), such as home-based HIV testing and self-collection of dried blood spots (DBS) to assess adherence to antiretroviral drug regimens, has become an important tool to support clinical research because it can facilitate participant reach, lower participant burden, and reduce discomfort with attending research visits in clinic spaces. RBSC is common in sexual health clinical intervention trials to assess the impact of an intervention or program on primary and secondary outcomes. However, the products and strategies employed to successfully implement RBSC can vary widely across studies. The purpose of this narrative review is twofold. First, to provide an overview of currently available RBSC products, their attributes, and their suitability for various clinical research applications. Considerations for blood-based and volumetric absorptive microsampling collection products, as well as self-administered sexually transmitted infection testing and other specimen types, are described. Second, RBSC implementation considerations at each stage of the collection process are discussed primarily from the perspective of the authors' collective expertise and experience with RBSC in HIV prevention and treatment clinical research. Successful RBSC product selection and implementation require a multidisciplinary team approach that is participant-centered to achieve high return rates, and ample time should be allotted to address the complexities of the procedures and processes. This review of RBSC product and implementation considerations offers an actionable framework and roadmap when considering incorporation of RBSC into clinical trials research.

trial registrationN/A.

Indexed as

BiospecimenNarrative reviewRemote collectionSexual health

Identifiers

PMID42189458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.