ReviewTranslational stroke research2026
Neuroinflammation in Ischemic Stroke: Mechanisms, Systemic Interactions, and Therapeutic Targets.
Review in Translational stroke research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ischemic stroke is the second leading cause of death worldwide and its global burden is predicted to increase over the upcoming decades. Acute therapies primarily focus on recanalization of the occluded blood vessels by intravenous thrombolysis and endovascular thrombectomy, but these therapies are not suitable for all patients. Also, in case of successful reperfusion, there remains a risk of secondary tissue damage known as ischemia-reperfusion injury. Inflammation plays a crucial role in both the infarcted tissue and ischemia-reperfusion injury after stroke. Innate and adaptive immune systems may drive an exacerbated inflammatory response after stroke, impacting patients' outcome. Research in stroke pathophysiology and the role of the immune system after stroke suggests that outcome may be improved by using immune-based therapies preventing this secondary tissue damage. Here we display a comprehensive description of chronological immune events at the cellular and molecular levels in different compartments after stroke and discuss the potential neuroprotective role of regulatory T cells (T
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