Evidence map›Paper›PMID 42189388›Full record

ArticleScience China. Life sciences2026

Food processing-derived carbon dots disrupt male fertility via the gut-testis axis.

Peigen Chen, Menghui Ma, Yanqing Li, Xi Chen, Zhenhan Xu, Jintao Guo, Xinyi Hu, Linyan Lv, Jianhe Guo, Guihua Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Science China. Life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peigen Chen *Reproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Menghui Ma *Reproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Yanqing Li *Reproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Xi ChenGuangdong Provincial Key Laboratory of Sensing Technology and Biomedical Instrument, Guangzhou, 510655, China.
Zhenhan XuReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Jintao GuoReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Xinyi HuGuangdong Provincial Key Laboratory of Sensing Technology and Biomedical Instrument, Guangzhou, 510655, China.
Linyan LvReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Jianhe GuoGuangdong Provincial Key Laboratory of Sensing Technology and Biomedical Instrument, Guangzhou, 510655, China. guojianhe@mail.sysu.edu.cn.
Guihua LiuReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China. liuguihua@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon dots (CDs) are unintentionally formed during thermal processing of food and are emerging environmental pollutants that may pose health risks. We investigated the reproductive toxicity of food-derived CDs via the gut-testicular axis by exposing male mice to environmentally relevant doses (25 and 100 mg kg

Indexed as

Carbon Quantum DotsFertilityGastrointestinal MicrobiomeInfertility, MaleTestisAnimalsBlood-Testis BarrierIntestinal Barrier FunctionMaleMiceTestosteroneTestosteronecarbon dotsgut microbiotamale infertilitynanomaterial toxicityreproductive toxicology

Identifiers

PMID42189388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.