Evidence map›Paper›PMID 42189243›Full record

Observational studyWorld journal of urology2026

Perioperative hyperchloremia is associated with acute kidney injury in elderly patients undergoing bipolar plasmakinetic transurethral resection of the prostate: a prospective observational study.

Haitao Jia, Qihui Zheng, Luyang Zhang, Jiangtao Bai, Guilin Wang, Ting Guo, Qi Jin, Yutong Lu, Zhilong Dong, Zhiping Wang

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haitao JiaDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China.ORCID http://orcid.org/0000-0002-7991-9567
Qihui ZhengDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China.
Luyang ZhangDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China.
Jiangtao BaiDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China.
Guilin WangDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China.
Ting GuoDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China.
Qi JinDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China.
Yutong LuDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China.
Zhilong DongDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China. dzl19780829@163.com.ORCID http://orcid.org/0000-0002-4919-8164
Zhiping WangDepartment of Urology, Second Hospital & Clinical Medical School of Lanzhou University, Cuiying Gate 82#, Chengguan District, Lanzhou, 730030, Gansu, China. wangzplzu@163.com.ORCID http://orcid.org/0000-0002-8140-591X

Funding

Innovation Driven Engineering Project of Gansu Association for Science and Technology GXH20230817-5
6 · The paper itself

Abstract

backgroundBipolar transurethral resection of the prostate (TURP) utilizes 0.9% saline irrigation, which eliminates the risk of traditional TUR syndrome (hyponatremia) but may cause hyperchloremia due to absorption of supraphysiological chloride fluid. The incidence of hyperchloremia and its association with acute kidney injury (AKI) in this context remain poorly defined.

methodsIn this prospective observational study, 614 patients undergoing bipolar plasmakinetic TURP were categorized into Hyperchloremia (postoperative peak chloride ≥ 110 mmol/L) and Non-Hyperchloremia groups. The primary outcome was the incidence of postoperative AKI, defined according to KDIGO creatinine criteria. Secondary outcomes included AKI severity, clinical outcomes, and the association between hyperchloremia and a composite adverse outcome (ICU admission, mechanical ventilation, or renal replacement therapy).

resultsPostoperative plasma chloride levels were positively correlated with the volume of irrigation fluid absorbed (R

conclusionsHyperchloremia is a common and serious complication resulting from absorption of irrigation fluid during bipolar TURP. It is strongly associated with an increased incidence and severity of AKI and is an independent risk factor for major adverse outcomes. These findings advocate for perioperative chloride monitoring and further investigation of balanced irrigation fluids to improve patient safety.

trial registrationwww.chictr.org.cn ; identifier: ChiCTR2300079095; Date: December 25, 2023.

Indexed as

Acute Kidney InjuryChloridesPostoperative ComplicationsProstatic HyperplasiaTransurethral Resection of ProstateWater-Electrolyte ImbalanceAgedAged, 80 and overHumansIncidenceMaleProspective StudiesTherapeutic IrrigationChlorides0.9% salineAcute kidney injuryHyperchloremiaIrrigation fluid absorptionTransurethral resection of the prostate

Identifiers

PMID42189243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.