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ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Comprehensive scoliosis conservative rehabilitation for adolescent idiopathic scoliosis: effects on spinal deformity, physical function, and quality of life, with a parallel mediation analysis of core muscle endurance and pulmonary function.

Xin Li, Xuan Zhou, Juping Liang, Hong Yu, Qimeng Fan, Peijie Chen, Qing Du

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

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7 authors.

Xin Li *School of Exercise and Health, Shanghai University of Sport, Shanghai, China. lixin02@xinhuamed.com.cn.
Xuan Zhou *Department of Rehabilitation Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Juping Liang *Department of Rehabilitation Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Hong YuDepartment of Rehabilitation Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Qimeng FanDepartment of Rehabilitation Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Peijie Chen *School of Exercise and Health, Shanghai University of Sport, Shanghai, China. chenpeijie@sus.edu.cn.
Qing Du *Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. duqing@xinhuamed.com.cn.

Funding

Advanced Rehabilitation Medical Technology and Management Project of Shanghai Municipal Health Commission SHKFJS008AGeneral Program of National Natural Science Foundation of China 81972030Key Project of Yuanshen Rehabilitation Institute, Shanghai Jiao Tong University School of Medicine yskf2-23-1107-3
6 · The paper itself

Abstract

purposeThis prospective cohort study aimed to evaluate the effects of a comprehensive scoliosis conservative rehabilitation (CSCR) program on spinal deformity, physical function, and quality of life in patients with adolescent idiopathic scoliosis (AIS), to identify relevant influencing factors, and to examine the mediating mechanisms through which CSCR improves spinal deformity.

methodsPatients with AIS were followed from November 2018 to April 2025. According to the preferences of patients and their guardians, those who accepted CSCR were allocated to the intervention group, whereas those who declined structured training and chose routine observation/follow-up were allocated to the control group. Participants in both groups additionally received bracing if the Cobb angle was ≥ 25°. The primary outcome was the 6-month change in the major-curve Cobb angle. Secondary outcomes included core muscle endurance, pulmonary function, and angle of trunk rotation (ATR), among other measures.

resultsA total of 351 patients were enrolled, including 233 in the CSCR group and 118 in the control group. After 6 months, the CSCR group showed a significant reduction in Cobb angle, whereas the control group showed a slight increase; the therapeutic response rate was also significantly higher in the CSCR group (26.6% vs. 5.9%, P < 0.001). Significant improvements were also observed in ATR, core muscle endurance, pulmonary function parameters (FVC and FEV

conclusionCSCR effectively reduces the major-curve Cobb angle and improves therapeutic response, physical function, and quality of life in patients with mild AIS. Core muscle endurance and pulmonary function appear to be key mediating pathways through which CSCR improves spinal deformity.

trial registrationwww.chictr.org.cn, ChiCTR1800017943. Registered on August 24, 2018..

Indexed as

Adolescent idiopathic scoliosisCohort studyComprehensive scoliosis conservative rehabilitationCore muscle enduranceMediation analysisPulmonary functionSpinal deformity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.