Evidence map›Paper›PMID 42189180›Full record

ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2026

Influence of general orthodontic treatment need and of specific anterior malocclusions on oral health-related quality of life in children and adolescents with class II malocclusion : A cross-sectional multicenter cohort study.

Stefan Keß, Noah Frieder Nordblom, Laura Geim, Angelika Stellzig-Eisenhauer, Felix Kunz

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In one paragraph

Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Letter to editor regarding "Influence of general orthodontic treatment need and of specific anterior malocclusions on oral health-related quality of life in children and adolescents with class II malocclusion".Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefan KeßDepartment of Orthodontics, University Hospital Würzburg, Würzburg, Germany.
Noah Frieder NordblomDepartment of Orthodontics, University Hospital Würzburg, Würzburg, Germany. nordblom_n@ukw.de.
Laura GeimDepartment of Orthodontics, University Hospital Würzburg, Würzburg, Germany.
Angelika Stellzig-EisenhauerDepartment of Orthodontics, University Hospital Würzburg, Würzburg, Germany.
Felix KunzDepartment of Orthodontics, University Hospital Würzburg, Würzburg, Germany. kunz_f@ukw.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOral health-related quality of life (OHRQoL) is a patient-reported outcome measure (PROM) that assesses patients' subjective perception of their oral health status. Previous studies assessing the influence of malocclusions on OHRQoL revealed inconsistent results. This cross-sectional multicenter cohort study aimed to investigate the impact of general orthodontic treatment need (OTN) and of specific anterior malocclusions on OHRQoL and its subdomains in children and adolescents with class II malocclusion.

methodsThis study included 321 patients with class II malocclusion who required an initial orthodontic diagnosis. OHRQoL was assessed using the German version of the Child Oral Health Impact Profile (COHIP-G19). OTN was evaluated using the Dental Aesthetic Index (DAI) and the Index of Orthodontic Treatment Need (IOTN). To determine specific anterior malocclusions, overjet, overbite, anterior crowding, and anterior spacing were analyzed. Multiple linear regression analysis was performed to examine the effects of OTN and of the anterior malocclusions on OHRQoL and its subdomains, adjusted for demographic confounders (age, gender, and socioeconomic status).

resultsHigh values for OTN were significantly associated with poorer OHRQoL in patients with class II malocclusion. Multiple regression showed a significant effect of overjet and anterior crowding in the upper jaw on OHRQoL. No statistically significant associations were found between OHRQoL and anterior open bite, deep bite, or anterior spacing.

conclusionHigh general OTN as well as specific anterior malocclusions such as increased overjet and anterior crowding showed significant associations with OHRQoL in children and adolescents with class II malocclusion. In addition, other unmeasured factors likely play a distinctive role in determining OHRQoL.

Indexed as

Child Oral Health Impact ProfileCross-sectional multicenter cohort studyOral health statusPatient-reported outcome measureSubjective perception

Identifiers

PMID42189180

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.