Evidence map›Paper›PMID 42189171›Full record

ReviewPediatric radiology2026

Magnetic resonance elastography of the pediatric kidney: technical considerations and emerging clinical applications.

Suraj D Serai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Suraj D SeraiDivision of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA. serais@chop.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal fibrosis is a common pathway of chronic kidney injury in children and an important determinant of long-term outcomes in both native and transplanted kidneys. Current assessment relies heavily on biopsy, which is invasive, prone to sampling error, and challenging to repeat in pediatric patients. Magnetic resonance elastography (MRE) is a noninvasive imaging technique that quantifies tissue stiffness and has become an established biomarker for hepatic fibrosis; however, its application to the pediatric kidney remains less well defined. This review summarizes the principles of renal MRE with a focus on pediatric-specific technical considerations and practical implementation. We discuss patient preparation, driver selection and positioning, sequence choices, image acquisition strategies, and common pitfalls unique to pediatric imaging. Methods for image analysis and interpretation are reviewed, with attention to confounding factors such as perfusion, inflammation, and hydration status. Emerging clinical applications are highlighted, particularly in pediatric kidney transplantation, where early detection and longitudinal monitoring of interstitial fibrosis and tubular atrophy may complement existing surveillance strategies. Renal MRE is a feasible and promising adjunct to pediatric renal MRI that can be implemented on modern clinical scanners. With continued technical refinement and validation, MRE has the potential to play an important role in noninvasive assessment of pediatric kidney disease.

Indexed as

ElastographyKidney MRIMRERenal MREStiffnessTransplant

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.