Evidence map›Paper›PMID 42189143›Full record

ArticleJournal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Intravenous Administration of Vitamin K1 in Dogs and Cats Presented for Anticoagulant Rodenticide Poisoning: A Retrospective Study of 58 Cases.

Camille Dartencet, Céline Pouzot-Nevoret, Marine Poupon, Mark W Kim, Bernard Allaouchiche, Alexandra Nectoux

Abstract read
In one paragraph

Article in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camille DartencetUniversité De Lyon, VetAgro Sup, Campus vétérinaire de Lyon, Intensive Care Unit (SIAMU), APCSe, Marcy-l'Etoile, France.
Céline Pouzot-NevoretUniversité De Lyon, VetAgro Sup, Campus vétérinaire de Lyon, Intensive Care Unit (SIAMU), APCSe, Marcy-l'Etoile, France.
Marine PouponUniversité De Lyon, VetAgro Sup, Campus vétérinaire de Lyon, Intensive Care Unit (SIAMU), APCSe, Marcy-l'Etoile, France.
Mark W KimUniversité De Lyon, VetAgro Sup, Campus vétérinaire de Lyon, Intensive Care Unit (SIAMU), APCSe, Marcy-l'Etoile, France.
Bernard AllaouchicheUniversité De Lyon, VetAgro Sup, Campus vétérinaire de Lyon, APCSe, Marcy-l'Étoile, France.
Alexandra NectouxUniversité De Lyon, VetAgro Sup, Campus vétérinaire de Lyon, Intensive Care Unit (SIAMU), APCSe, Marcy-l'Etoile, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the safety of IV lecithin-solubilizing agent-based vitamin K1 (VK-LSE) administration and compare the outcomes in dogs and cats with anticoagulant rodenticide (AR) poisoning that received IV VK-LSE with or without exogenous coagulation factors (CF).

designRetrospective study (January 2010 to January 2022).

settingUniversity teaching hospital. ANIMALS: Forty-seven dogs and 11 cats.

interventionsNone. MEASUREMENTS AND MAIN

resultsMedical records from dogs and cats diagnosed with AR poisoning were reviewed. Fifty-eight patients received VK-LSE (5 mg/kg, IV). Two groups, animals that received VK-LSE without CF (VK group) and animals that received VK-LSE and CF (VK-CF group), were identified. No adverse effects were recorded after IV VK-LSE administration. Twenty-nine of 58 patients received exogenous CF. No patient received fresh frozen plasma. All patients had coagulation times within reference intervals by 24 h following admission. There was no difference in survival to discharge for dogs (96% VK vs. 85% VK-CF, p = 0.22) or for cats (100%, both groups) between groups.

conclusionIV administration of VK-LSE appears to be safe, with no reported adverse effects. In AR-poisoned dogs and cats, IV VK-LSE administration without exogenous CF appears to rapidly normalize coagulation times, with high survival rates and short hospitalization lengths.

Indexed as

AnticoagulantsCat DiseasesDog DiseasesPoisoningRodenticidesVitamin K 1Administration, IntravenousAnimalsCatsDogsFemaleMaleRetrospective StudiesAnticoagulantsRodenticidesVitamin K 1anaphylaxisbleedingcoagulopathyphytomenadionerat baittransfusion

Identifiers

PMID42189143
PMCPMC13350224

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.