ArticleJACC. Case reports2026
From Nonobstructive Plaque to LAD Thrombosis in a 26-Year-Old Athlete.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
backgroundStimulants and anabolic steroids have a role in plaque disruption resulting in acute coronary syndrome in young adults. CASE SUMMARY: A 26-year-old bodybuilder with heavy use of anabolic steroids and energy drinks presented with chest pain and ST-segment changes. Coronary angiography revealed minimal nonobstructive plaque in the proximal left anterior descending artery and left ventricular systolic dysfunction. He was started on guideline-directed medical therapy and counseled to discontinue toxic exposures. Weeks later, he presented with recurrent chest pain and was found to have an acute thrombotic occlusion of the mid-left anterior descending artery requiring urgent revascularization and a drug-eluting stent placement. DISCUSSION: This case highlights how synergistic stimulant and anabolic exposure can create dynamic coronary pathology and contribute to endothelial injury, hypercoagulability, and accelerated atherosclerosis. TAKE-HOME MESSAGES: Nonobstructive coronary findings do not exclude imminent coronary thrombosis in high-risk young adults. Risk factor cessation and close follow-up are essential.
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