Evidence map›Paper›PMID 42188954›Full record

ReviewVeterinary sciences2026

Application of Gene Editing Technology in Poultry.

Ruyu Liao, Rong Ran, Yixin Liu, Xinyi Zhou, Min Tan, Qigui Wang, Haiwei Wang, Xi Lan

Abstract readReview
In one paragraph

Review in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruyu LiaoCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Rong RanCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Yixin LiuCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Xinyi ZhouCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Min TanCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Qigui WangChongqing Academy of Animal Sciences, Chongqing 402460, China.
Haiwei WangChongqing Academy of Animal Sciences, Chongqing 402460, China.
Xi LanCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.ORCID 0009-0000-1203-2059

Funding

2025 Chongqing Municipal College Student Innovation and Entrepreneurship Training Program S202510635193Breeding of New Breeds (Synthetic Line) of High-Quality Chickens for Both Meat and Eggs cstc2021 jscx-gksbX0004Chongqing Academy of Science and Technology NW202209Chongqing Science and Enterprise Consortium Germplasm Resources Collection and Utilization and Variety Trial KQ202301National Natural Science Foundation of China 31802054the Fundamental Research Funds for the Central Universities XDJK2020C018
6 · The paper itself

Abstract

Gene editing technology, a revolutionary tool in molecular biology, enables precise modifications of genomic sequences and gene expression patterns, thereby conferring desired traits to cells or organisms. Since 2014, CRISPR/Cas9 has rapidly become the most widely used gene editing method in agricultural animals due to its high editing efficiency. Subsequently, the development of novel gene editing systems, such as base editors and prime editors, has provided enhanced precision and reduced off-target effects. These advancements have facilitated the transition of gene editing from laboratory research to clinical and agricultural applications. Gene editing has been extensively utilized to enhance production traits, improve disease resistance, facilitate disease detection, and establish disease models. This review outlines the development of gene editing technologies, discusses the advantages and limitations of key gene editing tools, and explores their applications in poultry. Furthermore, it examines the challenges and future prospects of gene editing in animal husbandry, including off-target effects, ethical concerns, and technical complexities.

Indexed as

animal breedingCRISPR/Cas9delivery vectorgene editingpoultry animals

Identifiers

PMID42188954
PMCPMC13211502

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.