Evidence map›Paper›PMID 42188889›Full record

ReviewVeterinary sciences2026

Integrative Therapies in Wound Healing in Small Animals: An Approach Beyond Traditional Medicine.

Jorge Kauã Vila Real Sampaio Santos, Esther Daniela de Sousa Costa, César Carneiro Linhares Fernandes, Annice Aquino Cortez, Arícia Débora Vasconcelos Fonsêca, Rodrigo Fonseca de Medeiros Guedes, Paulo Ricardo Monteiro Araújo

Abstract readReview
In one paragraph

Review in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jorge Kauã Vila Real Sampaio SantosCenter of Health Science, University of Fortaleza, Fortaleza 60811-905, CE, Brazil.ORCID 0009-0007-1125-0119
Esther Daniela de Sousa CostaCenter of Health Science, University of Fortaleza, Fortaleza 60811-905, CE, Brazil.ORCID 0009-0005-8661-842X
César Carneiro Linhares FernandesCenter of Health Science, University of Fortaleza, Fortaleza 60811-905, CE, Brazil.ORCID 0000-0001-6205-7086
Annice Aquino CortezCenter of Health Science, University of Fortaleza, Fortaleza 60811-905, CE, Brazil.ORCID 0000-0002-6246-8122
Arícia Débora Vasconcelos FonsêcaCenter of Health Science, University of Fortaleza, Fortaleza 60811-905, CE, Brazil.ORCID 0000-0003-2240-7058
Rodrigo Fonseca de Medeiros GuedesCourse of Veterinary Medicine, Education, Sciences and Technology Center of the Inhamnuns Region, State University of Ceará, Tauá 63660-000, CE, Brazil.ORCID 0000-0002-2856-1235
Paulo Ricardo Monteiro AraújoCenter of Health Science, University of Fortaleza, Fortaleza 60811-905, CE, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin represents the largest organ in the body and functions to protect internal tissues from damage and infection. When wounds in small animals do not receive proper management, they may progress to chronic conditions, resulting in pain, delayed healing, and impaired well-being. Although conventional treatment mainly includes the use of topical antimicrobial agents and anti-inflammatory drugs, integrative veterinary medicine has been considered a promising complementary approach to enhance tissue repair. In this context, this study aimed to review non-conventional therapies applied to wound management in small animals, focusing on ozone therapy, light therapy that stimulates cellular activity, herbal medicine, and apitherapy, especially propolis. Overall, the analyzed studies indicate that ozone may contribute to microbial control and modulation of the immune response; light therapy may stimulate cellular activity and collagen production, promoting healing; medicinal plants present antioxidant and anti-inflammatory effects; and propolis demonstrates antimicrobial and regenerative properties. Thus, when responsibly applied and supported by scientific evidence, these approaches may complement conventional therapy, broaden clinical possibilities, and contribute to improved recovery and quality of life in animals.

Indexed as

integrative medicinelight therapymedicinal plantsozonepropoliswounds

Identifiers

PMID42188889
PMCPMC13211445

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.