Evidence map›Paper›PMID 42188819›Full record

ArticleVaccines2026

The Maternal Vaccine Study Protocol: A Victorian Cohort Study Evaluating Infant and Childhood Safety and Health and Developmental Outcomes After Vaccination Against Respiratory Viruses in Pregnancy.

Rachael Purcell, Margie Danchin, Nigel W Crawford, Eric Zhao, Ashleigh Rak, Michelle L Giles, Jim Buttery

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rachael PurcellEpidemiology Informatics, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia.
Margie DanchinDepartment of Paediatrics, The University of Melbourne, Melbourne, VIC 3010, Australia.
Nigel W CrawfordDepartment of Paediatrics, The University of Melbourne, Melbourne, VIC 3010, Australia.
Eric ZhaoEpidemiology Informatics, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia.ORCID 0000-0002-1246-2718
Ashleigh RakVaccine Trials and Uptake Group, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia.
Michelle L GilesDepartment of Obstetrics and Gynaecology, Monash University, Melbourne, VIC 3168, Australia.ORCID 0000-0003-3007-1822
Jim ButteryEpidemiology Informatics, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia.ORCID 0000-0001-9905-2035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesChanges in public policy are eroding vaccine confidence. Previously accepted peer-reviewed evidence around vaccination and developmental outcomes for children is being questioned. Robust, methodologically sound safety data are more needed than ever to maintain consumer confidence. Establishing further safety data on infant health, development, and allergies after COVID-19 and influenza vaccination in pregnancy may improve confidence and acceptance.

methodsThis is a state-wide multi-centre prospective cohort study conducted as a sub-study of the Generation Victoria birth cohort. It will examine the risk difference for infant health, developmental, and allergy outcomes between groups of mother-baby pairs who will be examined according to exposure (vaccination against a respiratory virus during pregnancy) and comparator (no vaccination against a respiratory virus).

resultsData contributing to the analysis include GenV-collected developmental, health, and allergy outcomes to 12 months of age, as well as data from state-wide linked datasets.

conclusionsThis linked-data longitudinal study will provide information on health, allergy, and developmental outcomes for infants in the first year of life after influenza and COVID-19 vaccination during pregnancy. IMPLICATIONS FOR PUBLIC HEALTH: The reporting of developmental data will be a new contribution to knowledge around outcomes after vaccination during pregnancy.

Indexed as

allergydevelopmentinfant healthmaternal vaccinationpregnancyvaccine

Identifiers

PMID42188819
PMCPMC13211398

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.