ArticleNeurology international2026
Cognitive and Histological Methodological Framework for an Intrahippocampal Aβ
Article in Neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
backgroundStandardized and ethically compliant animal models remain essential for improving translational research in Alzheimer's disease. Although Aβ
methodsWe explored the feasibility of a stereotactic intrahippocampal Aβ
resultsThe surgical procedure was well-tolerated, and the injected animals showed reduced performance in behavioural testing, including reduced spatial recognition memory in the Y-maze and decreased discrimination indices in the NOR test. The animals also showed histological changes, including Congo red-positive birefringent structures consistent with amyloid-like congophilic material.
conclusionsThis study presents a feasible experimental framework for intrahippocampal Aβ
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