Evidence map›Paper›PMID 42188322›Full record

ArticleMarine drugs2026

Equinatoxin II: How a Cationic Pore-Forming Sea Anemone Toxin Drives Nodal Swelling of Myelinated Nerve Fibers.

Evelyne Benoit, Robert Frangež, Gilles Ouanounou, Frédéric A Meunier, Dusan Šuput, Jordi Molgó

Abstract read
In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Evelyne BenoitService d'Ingénierie Moléculaire Pour la Santé (SIMoS), EMR CNRS 9004, Département Médicaments et Technologies Pour la Santé (DMTS), Institut des Sciences du Vivant Frédéric Joliot, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université Paris-Saclay, F-91191 Gif-sur-Yvette, France.ORCID 0000-0001-5501-0888
Robert FrangežInstitute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, S-1000 Ljubljana, Slovenia.ORCID 0000-0002-0636-9277
Gilles OuanounouUMR CNRS 9197, Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Saclay, F-91400 Saclay, France.
Frédéric A MeunierClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, School of Biomedical Sciences, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0001-6400-1107
Dusan ŠuputInstitute of Pathophysiology, Faculty of Medicine, University of Ljubljana, S-1000 Ljubljana, Slovenia.ORCID 0000-0003-4031-7267
Jordi MolgóService d'Ingénierie Moléculaire Pour la Santé (SIMoS), EMR CNRS 9004, Département Médicaments et Technologies Pour la Santé (DMTS), Institut des Sciences du Vivant Frédéric Joliot, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université Paris-Saclay, F-91191 Gif-sur-Yvette, France.ORCID 0000-0002-0693-8994

Funding

Bilateral Slovenian/French Proteus Program BI-FR-26-27-PROTEUS- 490 008The Slovenian Research and Innovation Agency P4-0053 and P3-0019
6 · The paper itself

Abstract

This study was performed to elucidate the mechanism underpinning the nodal swelling induced by equinatoxin II (EqtII), a cation-selective pore-forming toxin derived from the sea anemone

Indexed as

Cnidarian VenomsNerve Fibers, MyelinatedSea AnemonesAnimalsAxonsCalciumOsmotic PressureSodiumSodium-Calcium ExchangerCalciumCnidarian VenomsequinatoxinSodiumSodium-Calcium Exchangeraxonal swellingcationic pore-forming peptideconfocal laser scanning microscopyequinatoxin IIionic mechanismsmyelinated nerve fiber

Identifiers

PMID42188322
PMCPMC13208999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.