Evidence map›Paper›PMID 42188290›Full record

ArticleMarine drugs2026

Marine Antimicrobial Peptide as a Promising Alternative to Polymyxin B.

Victoria N Safronova, Vladislav A Lushpa, Victoria O Shipunova, Marta V Volovik, Kira L Dobrochaeva, Roman N Kruglikov, Ilia A Bolosov, Dmitrii E Dashevskii, Alexey V Mishin, Oleg V Batishchev and 7 more

Abstract read
In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. TheInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Victoria N SafronovaM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-2695-0157
Vladislav A LushpaM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-1788-1153
Victoria O ShipunovaM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-6361-1042
Marta V VolovikFrumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0002-0155-4414
Kira L DobrochaevaM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-4778-344X
Roman N KruglikovM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Ilia A BolosovM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-3539-4906
Dmitrii E DashevskiiMoscow Center for Advanced Studies, 123592 Moscow, Russia.
Alexey V MishinMoscow Center for Advanced Studies, 123592 Moscow, Russia.ORCID 0000-0003-3759-380X
Oleg V BatishchevFrumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0002-9581-2233
Olga V KorobovaState Research Center for Applied Microbiology & Biotechnology, 142279 Obolensk, Russia.
Alexander I BorzilovState Research Center for Applied Microbiology & Biotechnology, 142279 Obolensk, Russia.ORCID 0000-0001-6309-7645
Gulsara A SlashchevaBranch of M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
Igor A DyachenkoBranch of M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-3053-2804
Eduard V BocharovM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-3635-1609
Pavel V PanteleevM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-8448-031X
Tatiana V OvchinnikovaM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-5950-249X

Funding

Russian Science Foundation 22-14-00380-P
6 · The paper itself

Abstract

The rise in antimicrobial resistance represents a significant challenge to global health. The reason partially lies in an inappropriate use of conventional antibiotics and the subsequent rapid spread of multidrug-resistant pathogen strains. This emergency requires an urgent search for conceptually new antimicrobial agents. A viable alternative to conventional antibiotics is antimicrobial peptides (AMPs), which are ribosomally synthesized molecules with considerable potential as next-generation anti-infectious therapeutics. Previously, we have reported on the β-hairpin peptide Ap9, an analog of abarenicin from the marine polychaeta

Indexed as

Anti-Bacterial AgentsAntimicrobial PeptidesPolymyxin BAnimalsAquatic OrganismsDrug Resistance, BacterialEscherichia coliGram-Negative BacteriaLipopolysaccharidesMicrobial Sensitivity TestsAnti-Bacterial AgentsAntimicrobial PeptidesLipopolysaccharidesPolymyxin Bantibioticantimicrobial peptidedrug resistanceGram-negative bacteriain vivo studieslipopolysaccharidepolymyxin

Identifiers

PMID42188290
PMCPMC13208921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.