Evidence map›Paper›PMID 42188079›Full record

ArticleJournal of cardiovascular development and disease2026

How I Do It: Perioperative Use of Micro-Axial Pumps in High Risk Coronary Artery Bypass Grafting: The Early Johns Hopkins Experience.

Salman Zaheer, Mohammad Aref, Oldrich Virag, Bogdan Ivanov, Chetan Pasrija, Antonio Polanco, Hamza Aziz, Ahmet Kilic

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Salman ZaheerDivision of Cardiac Surgery, Penn State Milton S. Hershey Medical Center, 200 Campus Dr., Hershey, PA 17033, USA.
Mohammad ArefDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Oldrich ViragPenn State College of Medicine, 700 HMC Crescent Rd, Hershey, PA 17033, USA.ORCID 0009-0003-4135-7321
Bogdan IvanovPenn State College of Medicine, 700 HMC Crescent Rd, Hershey, PA 17033, USA.ORCID 0009-0002-5454-1438
Chetan PasrijaDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Antonio PolancoDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Hamza AzizDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Ahmet KilicDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA.ORCID 0000-0002-2365-3093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with left ventricular dysfunction undergoing cardiac surgery face a heightened risk of perioperative complications, including postcardiotomy shock (PCS). Conventional management with inotropes and vasopressors can exacerbate end-organ dysfunction, underscoring the need for alternative strategies. The planned use of mechanical circulatory support (MCS) devices, such as the Impella, offers a proactive approach to mitigating PCS in high-risk patients. This study presents our early experience at Johns Hopkins with planned Impella utilization in high-risk cardiac surgery. We detail our risk stratification methodology, patient selection criteria, and perioperative management strategies. Our proposed risk stratification scoring system incorporates surgical intent, preoperative myocardial function, anticipated postoperative course, and exit strategy to identify optimal candidates for perioperative MCS. We describe the intraoperative central placement technique for the Impella 5.5, perioperative management protocols-including anticoagulation strategies and weaning protocols-and postoperative device extraction. A retrospective review of our first 11 consecutive patients with severely reduced left ventricular ejection fraction (<30%) who underwent Impella-assisted cardiac surgery demonstrated favorable outcomes, with no postoperative mortality and a two-year follow-up. Our findings suggest that planned Impella use in high-risk cardiac surgery is both feasible and beneficial. However, further studies are necessary to validate these results, assess long-term outcomes, and evaluate cost-effectiveness.

Indexed as

cardiac surgeryImpella 5.5left ventricular dysfunctionmechanical circulatory supportmicroaxial pumpperioperative supportpostcardiotomy shock

Identifiers

PMID42188079
PMCPMC13206777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.