Evidence map›Paper›PMID 42188016›Full record

ArticleMetabolites2026

Association Between Sperm Metabolites and Field Fertility in Angus Bulls.

Samantha R Roberts, Sarah E Moorey, Adella B Lonas, Emma A Hessock, Blessing A Abiodun, Shawn R Campagna, F Neal Schrick, Saulo Menegatti Zoca

Abstract read
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In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samantha R RobertsDepartment of Animal Science, University of Tennessee Institute of Agriculture and AgResearch, 2506 River Drive, Knoxville, TN 37996, USA.
Sarah E MooreyDepartment of Animal Science, University of Tennessee Institute of Agriculture and AgResearch, 2506 River Drive, Knoxville, TN 37996, USA.ORCID 0000-0001-9243-3863
Adella B LonasDepartment of Animal Science, University of Tennessee Institute of Agriculture and AgResearch, 2506 River Drive, Knoxville, TN 37996, USA.
Emma A HessockDepartment of Animal Science, University of Tennessee Institute of Agriculture and AgResearch, 2506 River Drive, Knoxville, TN 37996, USA.
Blessing A AbiodunDepartment of Chemistry, University of Tennessee, 1420 Circle Dr., Knoxville, TN 37996, USA.ORCID 0009-0009-3370-6468
Shawn R CampagnaDepartment of Chemistry, University of Tennessee, 1420 Circle Dr., Knoxville, TN 37996, USA.ORCID 0000-0001-6809-3862
F Neal SchrickDepartment of Animal Science, University of Tennessee Institute of Agriculture and AgResearch, 2506 River Drive, Knoxville, TN 37996, USA.ORCID 0000-0003-0270-4127
Saulo Menegatti ZocaDepartment of Animal Science, University of Tennessee Institute of Agriculture and AgResearch, 2506 River Drive, Knoxville, TN 37996, USA.ORCID 0000-0002-5272-9405

Funding

National Association of Animal Breeders NAAB Doak Graduate Fellowship
6 · The paper itself

Abstract

BACKGROUND/

objectivesUnderstanding the causes of bull subfertility and developing reliable diagnostic tools are critical to reducing economic losses caused by reproductive failure in beef cattle. Metabolomic analysis of sperm from bulls with diverging field fertility may provide insights on sperm metabolism that are associated with fertility. The objective was to determine metabolomic differences in sperm from bulls with differing field fertility.

methodsAngus bulls (

resultsA total of 75 metabolites were detected. Quadratic relationships with fertility were observed for kynurenine, xanthine, and ophthalmate. Tricarballylic acid and creatinine showed a negative linear relationship with fertility. When differences in metabolite abundance were assessed between the four highest and lowest fertility bulls,

conclusionsMetabolites kynurenine, xanthine, ophthalmate, tricarballylic acid, and creatinine are potential fertility markers to identify subfertile bulls from a breeding population. These metabolites have promising future implications in the diagnosis and treatment of beef bull subfertility.

Indexed as

bull fertilitymetabolitesoxidative stresssperm

Identifiers

PMID42188016
PMCPMC13208153

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.