Evidence map›Paper›PMID 42187949›Full record

ArticleEntropy (Basel, Switzerland)2026

It Is What It Isn't: Introducing a Constraint-Based Approach to Structure Learning.

Christoffer Lundbak Olesen, Nace Mikuš, Mads Hansen, Nicolas Legrand, Peter Thestrup Waade, Christoph Mathys

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christoffer Lundbak OlesenInteracting Minds Centre, Aarhus University, Jens Chr. Skous Vej 4, 8000 Aarhus, Denmark.ORCID 0000-0002-7974-1463
Nace MikušInteracting Minds Centre, Aarhus University, Jens Chr. Skous Vej 4, 8000 Aarhus, Denmark.ORCID 0000-0002-3445-9464
Mads HansenDepartment of Philosophy, University of Bristol, Cotham House, Bristol BS6 6JL, UK.ORCID 0009-0009-9133-3751
Nicolas LegrandInteracting Minds Centre, Aarhus University, Jens Chr. Skous Vej 4, 8000 Aarhus, Denmark.ORCID 0000-0002-2651-4929
Peter Thestrup WaadeTranslational Neuromodeling Unit, University of Zürich and ETH Zürich, Wilfriedstrasse 6, 8032 Zürich, Switzerland.ORCID 0000-0002-6061-0084
Christoph MathysInteracting Minds Centre, Aarhus University, Jens Chr. Skous Vej 4, 8000 Aarhus, Denmark.ORCID 0000-0003-4079-5453

Funding

Aarhus Universitets Forskningsfond AUFF-E-2019-7-10Carlsberg Foundation CF21-0439Danmarks Frie Forskningsfond 3166-00158BWellcome Trust 226776/Z/22/Z
6 · The paper itself

Abstract

Biological cognition depends on learning-structured representations in ambiguous environments. Computational models of structure learning typically frame this as an inference problem, but often overlook the temporally extended dynamics that shape learning trajectories under ambiguity. In this paper, we reframe structure learning as an emergent consequence of constraint-based dynamics. Informed by the literature on the role of constraints in complex biological systems, we develop a constraint-based approach to computational cognitive modelling and provide a proof-of-concept model. The model consists of an ensemble of components, each comprising an individual learning process, whose internal updates are locally constrained by both external observations and system-level relational constraints. This is formalised using Bayesian probability as a description of constraint satisfaction rather than epistemic inference. Representational structure is not encoded directly in the model equations, but emerges over time through the interaction, stabilisation, and elimination of components under these constraints. Through a series of simulations in environments with varying degrees of ambiguity, we demonstrate that the model reliably differentiates the observation space into stable representational categories. We further analyse how global parameters controlling internal constraint and initial component precision shape learning trajectories and long-term behavioural alignment with the environment. We discuss the formal relationship between the present approach and Bayesian inference accounts, and argue that a constraint-based approach offers a conceptually distinct foundation for relating computational models to biological systems.

Indexed as

cognitive modellingcomputational psychiatryconstraint-based dynamicsdelusionshierarchical Gaussian filterstructure learning

Identifiers

PMID42187949
PMCPMC13206405

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.