Evidence map›Paper›PMID 42187874›Full record

ArticleDiseases (Basel, Switzerland)2026

Post-Vaccination Surveillance of Invasive Pneumococcal Disease in Ghana.

Fleischer C N Kotey, Reuben E Arhin, Nicholas T K D Dayie, Emmanuel O Ampah, Abass Abdul-Karim, Deric A Baah, Ruth M Afful, Georgina Tetteh-Ocloo, Roland T Kom-Zuta, Francis K M Tetteh and 7 more

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Article in Diseases (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Fleischer C N KoteyDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0003-0286-3638
Reuben E ArhinDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0002-5726-4694
Nicholas T K D DayieDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0003-4491-6902
Emmanuel O AmpahDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.
Abass Abdul-KarimZonal Public Health and Reference Laboratory, Tamale P.O. Box TL 99, Ghana.
Deric A BaahDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.
Ruth M AffulDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.
Georgina Tetteh-OclooDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.
Roland T Kom-ZutaDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.
Francis K M TettehDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0001-9522-8320
Mary-Magdalene OseiDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0002-2216-7237
Yvonne N A BrewGreater Accra Regional Hospital, Accra P.O. Box 473, Ghana.
Mame Y NyarkoPrincess Marie Louise Children's Hospital, Accra P.O. Box GP 122, Ghana.
Karikari Asafo-AdjeiHo Regional Hospital, Ho P.O. Box MA 374, Ghana.
Patience B Tetteh-QuarcooDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.ORCID 0000-0002-3344-4869
Edem M A TetteDepartment of Community Health, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.
Eric S DonkorDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, Accra P.O. Box KB 4236, Ghana.

Funding

Pfizer Pharmaceuticals, USA. 56833225
6 · The paper itself

Abstract

background

aimTo describe the post-vaccination epidemiology of invasive pneumococcal disease (IPD) in Ghana, including the prevalence, serotype distribution and antibiotic resistance.

methodsThe study was cross-sectional and involved 14,597 patients recruited at the Korle Bu Teaching Hospital, Greater Accra Regional Hospital, Princess Marie Louise Children's Hospital, Ho Regional Hospital, Eastern Regional Hospital, and Zonal Public Health and Reference Laboratory, Tamale. Specimens of cerebrospinal fluid (obtained by lumbar puncture) and blood were collected routinely from meningitis patients, while blood specimens were taken from pneumonia patients. These were cultured for

resultsThe overall prevalence of IPD was 0.66% (

conclusionsEven in the post-vaccination era, vaccine-type IPD remains a significant public health issue in Ghana. The observed serotype distribution and antimicrobial resistance patterns warrant sustained surveillance, more adaptive vaccination policies, and rigorous antibiotic stewardship to effectively mitigate IPD burden.

Indexed as

antimicrobial resistanceGhanainvasive pneumococcal diseasepost-vaccination epidemiologyserotype distributionStreptococcus pneumoniae

Identifiers

PMID42187874
PMCPMC13205543

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