ReviewJournal of fungi (Basel, Switzerland)2026
Relationship Between Onychomycosis and HIV: A Systematic Review.
Review in Journal of fungi (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesOnychomycosis is a fungal nail infection that may present with severe, atypical, or treatment-resistant features in people living with HIV. Despite its clinical importance, evidence regarding its epidemiology, causative agents, and relationship with immune status remains limited. This systematic review aimed to evaluate the association between onychomycosis and HIV, focusing on prevalence, clinical characteristics, etiologic agents, and CD4+ T lymphocyte counts at diagnosis.
methodsA systematic review was conducted following PRISMA guidelines. MEDLINE/PubMed, SciELO, Scopus, and Scilit were searched for studies published between October 2015 and July 2025 in English and Spanish. Eligible studies included case reports, case series, and observational studies involving people with HIV and confirmed onychomycosis. Data extraction was performed independently, and findings were analyzed descriptively.
resultsThirty studies comprising 1296 patients were included; 306 had detailed clinical descriptions. Most cases were reported in the Americas (85.8%) and predominantly involved male patients. CD4+ counts were available in 123 individuals; 52% had <200 cells/µL, including 18 with <50 cells/µL.
conclusionsOnychomycosis in HIV shows etiologic diversity and commonly affects patients with advanced immunosuppression, though it may also occur with partial immune preservation. Prospective standardized studies are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.