ArticleBiology2026
Gut Microbiota Mediates Host Responses to Microplastic Exposure in
Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundMicroplastics, derived from plastic degradation and industrial sources, are widely detected in aquatic environments and food systems, posing increasing environmental and ecological risks.
aimsThis study aimed to investigate how microplastics affect host physiology and gut microbiota, as well as determine whether microbiota changes actively modulate host responses.
methodsUsing
resultsPolystyrene microplastics accumulated in the gut and significantly impaired growth and survival, accompanied by reduced digestive enzyme activity and immune function, as well as increased oxidative stress, indicating disruption of physiological homeostasis. Microplastic exposure also induced microbial dysbiosis, characterized by decreased diversity and compositional shifts. Functional assays demonstrated that a bacterium enriched under exposure,
conclusionsThese findings demonstrate that gut microbiota are not only altered by microplastic exposure but also actively modulate host responses to environmental stress, providing new insight into microbiota-mediated resilience under pollutant stress.
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What OpenQuestion holds
Registered trials
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