Evidence map›Paper›PMID 42187702›Full record

ArticleBiology2026

Apigenin Attenuates Paroxetine-Induced Ovarian Alterations in Female Rats.

Nazife Ulker Ertugrul, Tugrul Ertugrul, Feyza Keskin Buyukbudak, Ebru Gokdere, Meryem Sedef Dogru, Serife Tutuncu, Sinan Canpolat

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nazife Ulker ErtugrulDepartment of Physiology, Faculty of Medicine, Samsun University, 55080 Samsun, Turkey.ORCID 0000-0002-3805-2362
Tugrul ErtugrulDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Ondokuz Mayıs University, 55200 Samsun, Turkey.
Feyza Keskin BuyukbudakDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Ondokuz Mayıs University, 55200 Samsun, Turkey.
Ebru GokdereExperimental Research Center, Firat University, 23119 Elazig, Turkey.ORCID 0000-0002-5864-4146
Meryem Sedef DogruDepartment of Physiology, Faculty of Medicine, Firat University, 23119 Elazig, Turkey.
Serife TutuncuDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Ondokuz Mayıs University, 55200 Samsun, Turkey.ORCID 0000-0001-6834-7244
Sinan CanpolatDepartment of Physiology, Faculty of Medicine, Dokuz Eylul University, 35220 Izmir, Turkey.

Funding

the Samsun University Scientific Research Projects Management Unit, Samsun, Turkey BAP.TIP.5501.2024.001
6 · The paper itself

Abstract

Paroxetine, a selective serotonin reuptake inhibitor commonly used to treat various psychiatric disorders, may adversely affect female reproductive function. Although apigenin has been shown to ameliorate reproductive abnormalities and ovarian dysfunction, its effect on paroxetine-induced reproductive toxicity in females remains unclear. Therefore, this study investigated the potential protective effects of apigenin against paroxetine-induced reproductive alterations in female rats. Female rats with regular estrous cycles were randomly assigned to four groups (

Indexed as

AMHapigeninfemale reproductive toxicityiNOSovaryparoxetineratVEGF

Identifiers

PMID42187702
PMCPMC13203083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.