Evidence map›Paper›PMID 42187613›Full record

ReviewCurrent oncology (Toronto, Ont.)2026

Cancer During Pregnancy: Navigating Clinical and Research Challenges.

Mackenzie K Callaway, Lizelle Comfort, Dhivyaa Anandan, Ruby Sharma, Narjust Florez, Traci R Lyons, Doris Germain, Kathleen R Cho, Burton L Rochelson, Clarissa Bonanno and 13 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Women's Health in Oncology.Pharmacotherapy · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Mackenzie K CallawayCancer Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Lizelle ComfortDepartment of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Northwell Health and Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, New Hyde Park, NY 11042, USA.ORCID 0000-0002-1507-0656
Dhivyaa AnandanCancer Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.ORCID 0000-0001-8272-8756
Ruby SharmaNorthwell Health Cancer Institute, 1111 Marcus Avenue, New Hyde Park, NY 11042, USA.
Narjust FlorezDana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.ORCID 0000-0002-7814-1773
Traci R LyonsDepartment of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Doris GermainTisch Cancer Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Kathleen R ChoDepartment of Pathology, The University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Burton L RochelsonDepartment of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Northwell Health and Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, New Hyde Park, NY 11042, USA.ORCID 0000-0002-6736-1105
Clarissa BonannoDepartment of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Northwell Health and Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, New Hyde Park, NY 11042, USA.
Kutluk OktayDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.
Sudarshana RoychoudhuryDepartment of Pathology and Laboratory Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Greenvale, NY 11549, USA.
Eileen O'donnellNorthwell Health Cancer Institute, 1111 Marcus Avenue, New Hyde Park, NY 11042, USA.
Richard BarakatNorthwell Health Cancer Institute, 1111 Marcus Avenue, New Hyde Park, NY 11042, USA.
Joanne MarquardtBabylon Breast Cancer Coalition, 218N Wellwood Ave Suite #2, Lindenhurst, NY 11757, USA.
Diana W BianchiPrenatal Genomics and Therapy Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, 35A Convent Drive, Bethesda, MD 20892, USA.
Elyce CardonickDepartment of Obstetrics and Gynecology, Cooper University Health Care, Camden, NJ 08103, USA.ORCID 0000-0003-2203-3367
Larry NortonDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Ann H PartridgeDana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
Susan M DomchekDepartment of Medicine, University of Pennsylvania Health System, Philadelphia, PA 19104, USA.
Virginia F BorgesDepartment of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Frédéric AmantDepartment of Oncology, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-5452-4905
Camila O Dos SantosCancer Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Funding

Blockade of cMYC oncogenic function by pregnancy-induced alterations and remodeling of the mammary glandR01CA284630 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Camila dos Santos · 2023 to 2026
$1.9M
NCI NIH HHS R01 CA284630
6 · The paper itself

Abstract

The incidence of cancer during pregnancy is rising, yet scientific understanding and clinical management remain underdeveloped. Delayed diagnoses, limited therapeutic options, and lack of safety data exacerbate the clinical challenges of treating cancer during pregnancy. Further, the biology of gestational cancers is poorly understood due to the scarcity of model systems and mechanistic studies. This manuscript presents a multidisciplinary perspective from a group of researchers and clinicians to evaluate the current state of pregnancy-associated cancers, identify unmet clinical and biological questions, and propose strategies to improve diagnosis, treatment, and maternal-fetal outcomes.

Indexed as

NeoplasmsPregnancy Complications, NeoplasticFemaleHumansPregnancycancercancer during pregnancyhealth disparitymaternal–fetal care

Identifiers

PMID42187613
PMCPMC13204943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.