Evidence map›Paper›PMID 42187484›Full record

ReviewBiosensors2026

Application of Rapid Detection Technology for the Determination of γ-Hydroxybutyric Acid.

Nan Li, Xingliang Liu, Boyuan Shi, Chunhui Song, Teng Zhang, Xin Yan, Yingying Li, Xinyi Li, Jun Ma

Abstract readReview
In one paragraph

Review in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nan LiBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.
Xingliang LiuBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.
Boyuan ShiBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.
Chunhui SongBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.
Teng ZhangBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.
Xin YanBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.
Yingying LiBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.
Xinyi LiBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.
Jun MaBeijing Key Laboratory of Psychoactive Substances Detection and Control, Beijing Narcotics Control Technology Center, Beijing 100164, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The abuse of γ-hydroxybutyric acid (GHB) and its precursors, γ-butyrolactone (GBL) and 1,4-butanediol (1,4-BD), has increased in recent years, with these substances frequently being illicitly added to beverages. GHB is colorless and odorless and exhibits anesthetic and hypnotic psychoactive effects, which are often exploited in drug-facilitated sexual assault, posing a significant public safety concern. Chromatography-tandem mass spectrometry is a conventional analytical approach for narcotic drug determination due to its high sensitivity and accuracy; however, its large instrumentation footprint and high operational cost limit its suitability for on-site rapid screening. In response to the growing demand for field-deployable analytical tools, rapid detection technologies for GHB have progressively evolved. This review summarizes and compares the advantages and limitations of current rapid detection methods for GHB and discusses their potential future developmental trends, with the aim of providing a reference for researchers and relevant authorities.

Indexed as

Biosensing TechniquesHydroxybutyratesHumansTandem Mass Spectrometry4-hydroxybutyric acidHydroxybutyratescolorimetric methodrapid detectionreviewγ-hydroxybutyric acid

Identifiers

PMID42187484
PMCPMC13205081

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.