Ultrasensitive Dopamine Detection in Undiluted Serum with a Disposable Electrochemical Sensor Employing MOF-Derived Gold Nanocomposites.

Rohan Sagar, Hsiao-Wei Wen, Ching-Chou Wu, M S Gaur

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Article in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

4 authors.

Rohan SagarDepartment of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, Taichung City 402, Taiwan.

Hsiao-Wei WenDepartment of Food Science and Biotechnology, National Chung Hsing University, Taichung City 402, Taiwan.ORCID 0000-0003-3427-1768

Ching-Chou WuDepartment of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, Taichung City 402, Taiwan.ORCID 0000-0002-8683-3796

M S GaurDepartment of Physics, Hindustan College of Science and Technology, Farah, Mathura 281122, Uttar Pradesh, India.

Funding

Ministry of Education framework of the Higher Education Sprout ProjectNational Science and Technology Council 113-2218-E-040 -001National Science and Technology Council 114-2321-B-005-004National Science and Technology Council NSTC112-2313-B-005-013-MY3National Science and Technology Council NSTC 113-2811-B-005-030

6 · The paper itself

Abstract

Dopamine (DA) is essential for motor control, motivation, and cognition, and its dysregulation is associated with neurological and psychiatric disorders such as Parkinson's disease, schizophrenia, and addiction. Accurate and selective DA quantification in complex biological matrices is important, but remains challenging because of coexisting interferents and the low physiological concentration of DA. Here, we report a disposable electrochemical DA sensor based on screen-printed carbon electrodes (SPCEs) modified with metal-organic framework-derived gold nanocomposites (MOFD-AuNCs). The optimal material, synthesized with a 60 min NaBH

Indexed as

Biosensing TechniquesDopamineElectrochemical TechniquesNanocompositesAnimalsCarbonElectrodesGoldHumansLimit of DetectionMetal NanoparticlesSwineCarbonDopamineGolddopamineelectrochemical sensorsMOF-derived gold nanocompositescreen-printed carbon electrodeundiluted serum

Identifiers

PMID42187451

DOI10.3390/bios16050255

PMCPMC13204897

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