Evidence map›Paper›PMID 42187445›Full record

ReviewBiosensors2026

Graphene Quantum Dot-Based Biosensors: Recent Advances in Functionalization Strategies and Biomedical Applications.

Mahnoush Beygisangchin, Jaroon Jakmunee, Nawee Kungwan, Kontad Ounnunkad, Padchanee Sangthong, Amir Hossein Baghdadi, Siti Kartom Kamarudin

Abstract readReview
In one paragraph

Review in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mahnoush BeygisangchinResearch Laboratory for Analytical Instrument and Electrochemistry Innovation, Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Jaroon JakmuneeResearch Laboratory for Analytical Instrument and Electrochemistry Innovation, Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Nawee KungwanResearch Laboratory for Analytical Instrument and Electrochemistry Innovation, Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Kontad OunnunkadResearch Laboratory for Analytical Instrument and Electrochemistry Innovation, Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Padchanee SangthongResearch Laboratory for Analytical Instrument and Electrochemistry Innovation, Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-8399-3367
Amir Hossein BaghdadiSchool of Engineering, Faculty of Engineering and Information Sciences, University of Wollongong, Wollongong, NSW 2522, Australia.
Siti Kartom KamarudinFuel Cell Institute, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia.

Funding

Chiang Mai University This work was supported by Fundamental Fund 2026, Chiang Mai University and Center of Excellence for Innovation in Chemistry. Partially supported by CMU Proactive Researcher Scheme (2024), Chiang Mai University is gratefully acknowledged.
6 · The paper itself

Abstract

Graphene quantum dots (GQDs) have emerged as a promising class of carbon-based nanomaterials owing to their unique optical properties, tunable surface chemistry, excellent biocompatibility, and high physicochemical stability. These features make GQDs particularly attractive for the development of advanced biosensing platforms. This review provides a comprehensive overview of recent progress in the design, synthesis, and functionalization of GQDs, with a primary focus on their applications in biomedical and biosensors. Various synthesis approaches, including top-down, bottom-up, and chemical methods, are critically discussed in relation to their impact on structural and optical properties. The role of surface engineering and heteroatom doping in modulating sensitivity, selectivity, and signal transduction mechanisms is also highlighted. Furthermore, recent advances in GQD-based biosensors for the detection of clinically relevant biomarkers, environmental analytes, and pathogens are systematically summarized, with emphasis on analytical performance metrics such as sensitivity, selectivity, and limit of detection. In addition, complementary biomedical applications, including bioimaging and therapeutic platforms, are briefly discussed to provide a broader context for the multifunctionality of GQDs. Finally, current challenges and future perspectives toward the rational design of high-performance GQD-based biosensors are outlined.

Indexed as

Biosensing TechniquesGraphiteQuantum DotsCarbon Quantum DotsHumansGraphitebiomedical nanocomposites and biosensing applicationsgraphene quantum dotsheteroatom and single-atom dopingphotodynamic and photothermal therapiesstructure–property–function relationship

Identifiers

PMID42187445
PMCPMC13205017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.