Evidence map›Paper›PMID 42187442›Full record

ReviewBiosensors2026

Carbon Dot-Based Electrochemical and Optical Sensors for Pharmaceutical Analysis and Point-of-Care Diagnostics.

Ganesh Gollavelli, Chiranjib Patra, Chiranjeevi Korupalli, Manuri Brahmayya, Yong-Chen Ling

Abstract readReview
In one paragraph

Review in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ganesh GollavelliDepartment of Chemistry, Aurora Deemed to be University, Hyderabad 500098, India.ORCID 0000-0001-8918-3269
Chiranjib PatraDepartment of Biological Sciences, School of Engineering and Sciences, SRM University-AP, Amaravati 522502, India.ORCID 0009-0003-3941-0074
Chiranjeevi KorupalliDepartment of Biological Sciences, School of Engineering and Sciences, SRM University-AP, Amaravati 522502, India.ORCID 0000-0002-8855-9938
Manuri BrahmayyaDepartment of Chemistry, Vallurupalli Nageswara Rao Vignana Jyothi Institute of Engineering and Technology, Hyderabad 500118, India.ORCID 0000-0001-6925-2423
Yong-Chen LingDepartment of Chemistry, National Tsing Hua University, Hsinchu 300044, Taiwan.ORCID 0000-0002-9903-8062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because of their special optical and electrochemical characteristics, superior biocompatibility, adjustable surface chemistry, and inexpensive, scalable synthesis, carbon dots (CDs), including carbon quantum dots and graphene quantum dots, have become powerful and adaptable nanomaterials for advanced pharmaceutical analysis and other toxicants. The sensitive and selective detection of active pharmaceutical substances, degradation products, contaminants, biomarkers, and therapeutic medication levels in complex matrices has shown great promise in recent years with CD-based nanobiosensors. The development of various sensing platforms, such as electrochemical, optical, and dual-mode biosensors, as well as integration into microfluidic, paper-based, and wearable point-of-care (POC) devices, is made possible by their intrinsic fluorescence, effective electron transfer capacity, and ease of functionalization. With an emphasis on sensing mechanisms, biorecognition techniques, and analytical performance, this study critically reviews current developments in CD-based nanobio/chemosensors for pharmaceutical analysis. It includes a thorough discussion of important applications in drug development, stability research, therapeutic drug monitoring, and drug quality control. Along with new developments like green synthesis, AI-assisted signal processing, and smart sensing platforms, current issues with reproducibility, standardization, biocompatibility, and regulatory validation are highlighted. Lastly, prospects for the industrial application and clinical translation of CD-based nanobiosensors are discussed.

Indexed as

Carbon Quantum DotsElectrochemical TechniquesBibliometricsBiosensing TechniquesElectrodesHumansPoint-of-Care SystemsWearable Electronic Devicescarbon dotscarbon quantum dotselectrochemical sensingnanobiosensorsoptical sensingpharmaceutical analysispoint-of-care testing

Identifiers

PMID42187442
PMCPMC13204412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.