Evidence map›Paper›PMID 42187391›Full record

ArticleBiomimetics (Basel, Switzerland)2026

V-CHIMERA: An Immune-Inspired Verified Framework for Organizational Cyber Crisis Response Under Misinformation.

Fahad Alghamdi, Saad Alqithami

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fahad AlghamdiComputer Science Department, Al-Baha University, Albaha 65779, Saudi Arabia.ORCID 0000-0002-4161-2658
Saad AlqithamiComputer Science Department, Al-Baha University, Albaha 65779, Saudi Arabia.ORCID 0000-0002-2111-3456

Funding

Cybersecurity Research and Innovation Pioneers Grants Initiative, provided by the National Cybersecurity Authority (NCA) CRPG-00-0000
6 · The paper itself

Abstract

In organizational cyber crises, incident response and official communication form coupled control loops, yet they are usually engineered separately. We present V-CHIMERA (Verified Coupled Human-Information-Machine Incident Response Architecture), a framework for organizational cyber crisis response under misinformation that jointly models cyber state, belief dynamics, trust, and communication governance. The framework combines three elements: an explicit cyber-social coupling architecture, a runtime protocol shield for communication safety, and immune-gated coupling (IGC) that uses danger signaling, tolerance thresholds, and immune memory to regulate when social feedback should affect operational response and how strongly counter-messaging should be targeted. Across three representative scenarios-ransomware rumor, outage rumor, and exfiltration scam-and eight seeds per scenario, all shielded policies achieved zero executed protocol violations. Relative to naive coupled control, IGC reduced cyber-harm area under the curve (AUC) by 57.6% in ransomware rumor and 42.6% in outage rumor while also reducing misbelief. Results were scenario-dependent rather than uniformly dominant: in exfiltration scam, a broadcast-only ablation outperformed targeted messaging, showing that targeting can fail when diffusion rapidly crosses community boundaries. Sensitivity analysis further shows that IGC attenuates the brittleness observed under strong coupling and weak moderation. The results suggest that biomimetic regulation is valuable not because coupling always helps, but because it prevents overreaction, clarifies when targeting should be used, and yields safer organizational defaults for misinformation-aware incident response.

Indexed as

artificial immune systemsbiomimeticscrisis communicationcyber incident responsedanger theorymisinformationmulti-agent systemsruntime enforcementsocial cybersecuritysocio-technical risk

Identifiers

PMID42187391
PMCPMC13204025

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.