ArticleMicrobiology spectrum2026
Hospital-wide pathogen transmission surveillance combining epidemiological, genetic, and spectroscopic approaches.
Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Nosocomial infections, particularly those caused by multidrug-resistant organisms, pose a significant challenge in healthcare facilities. This study presents a novel approach that combines tracking patient contacts in the hospital with Fourier-transform infrared (FTIR) spectroscopy and whole-genome sequencing (WGS) of bacterial isolates for rapid surveillance of nosocomial pathogen transmissions. Isolates from relevant species were collected over a 2-month period, and FTIR spectroscopy and WGS were performed on strains suspected in transmission events. The integrated approach identified 94 suspected transmission events involving 103 patients, with single nucleotide polymorphism analysis confirming 32% of these transmissions. FTIR spectroscopy demonstrated good specificity and moderate sensitivity compared to WGS, with the performance highly dependent on the bacterial species analyzed. Room contact of the patients played an important role in pathogen transmission, particularly with
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