Evidence map›Paper›PMID 42186997›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2026

A Holistically Engineered Laccase Nanozyme With Enhanced Activity for Phenolic Compound Removal.

Chi Xu, Mengying Tao, Jiahao Huang, Xuechun Wei, Zuyi Lu, Zhaorui Wang, Pinli Guo, Zhiguo Chen, Liqin Zhou, Zhenxia Zhao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chi XuGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Mengying TaoGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Jiahao HuangGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Xuechun WeiGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Zuyi LuGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Zhaorui WangGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Pinli GuoGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Zhiguo ChenGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Liqin ZhouGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.ORCID https://orcid.org/0009-0001-5658-2666
Zhenxia ZhaoGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
Zhongxing ZhaoGuangxi Key Laboratory of AI-Driven Zero-Carbon Technology, Key Laboratory of New Low-Carbon Green Chemical Technology, Education Department of Guangxi Zhuang Autonomous Region, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.ORCID https://orcid.org/0000-0002-3664-3476

Funding

Innovation Project of Guangxi Graduate Education YCBZ2025029National Natural Science Foundation of China 22268004Natural Science Foundation of Guangxi Province 2026GXNSFDA00640015
6 · The paper itself

Abstract

To achieve high catalytic activity in laccase-mimicking nanozymes, it is essential to accurately replicate the enzyme's active catalytic center and ensure effective transport of substrates and oxygen. To address this challenge, this work presents a holistic biomimetic strategy based on the natural laccase catalytic process, designing a novel nanozyme Cu-Cys@PCN-222(Cu/Fe). In this nanozyme, the incorporation of Cys and the FeTCPP into the PCN-222 framework achieves the biomimicry of the substrate binding pocket and oxygen-carrying hydrophobic sites, respectively. These two key components enables efficient pollutant enrichment and enhances dissolved oxygen capture and transport. Finally, Cys and TCPP within the PCN-222 framework through the coordination with copper constructed the CuN

Indexed as

LaccasePhenolsCatalysisCopperCopperLaccasePhenolscysteineFeTCPPnanozymePCN‐222phenolic pollutants

Identifiers

PMID42186997
PMCPMC13360785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.