Evidence map›Paper›PMID 42186857›Full record

ArticleACS synthetic biology2026

Engineering the

Xinyu Gong, Shuo Yu, Jiyang Zhang, Zebang Chen, Jianli Zhang, Qi Gan, Yajun Yan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS synthetic biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinyu GongSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, The University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0002-6111-5819
Shuo YuSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, The University of Georgia, Athens, Georgia 30602, United States.
Jiyang ZhangSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, The University of Georgia, Athens, Georgia 30602, United States.
Zebang ChenSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, The University of Georgia, Athens, Georgia 30602, United States.
Jianli ZhangSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, The University of Georgia, Athens, Georgia 30602, United States.
Qi GanSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, The University of Georgia, Athens, Georgia 30602, United States.
Yajun YanSchool of Chemical, Materials and Biomedical Engineering, College of Engineering, The University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0002-9993-3016

Funding

Engineering Dynamic Control of Natural Product Biosynthesis in BacteriaR35GM128620 · NIGMS · UNIVERSITY OF GEORGIA · PI Yajun Yan · 2018 to 2026
$3.0M
NIGMS NIH HHS R35 GM128620
6 · The paper itself

Abstract

The tricarboxylic acid (TCA) cycle is an essential part of the central metabolic hub that provides energy and biosynthetic precursors. Efficient regulation of central carbon flux is critical for maintaining optimal productivity of microbial cell factories (MCFs). However, biosensors capable of sensing TCA intermediates remain limited. Here, we engineered the catabolite control protein C (CcpC) from

Indexed as

BacillusBacterial ProteinsBiosensing TechniquesCitric AcidEscherichia coliRepressor ProteinsTranscription FactorsBinding SitesCitric Acid CyclePromoter Regions, GeneticProtein EngineeringBacterial Proteinscatabolite control proteins, bacteriaCitric AcidRepressor ProteinsTranscription Factorsbiosensorcatabolite control protein C (CcpC)citratehybrid promoterprotein engineeringtranscription factor (TF)

Identifiers

PMID42186857
PMCPMC13288900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.