ReviewPlant, cell & environment2026
Small Peptides, Smart Plants: The Emerging Significance of SCOOP Signalling.
Review in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Small Peptides, Smart Plants: The Emerging Significance of SCOOP Signalling.Plant, cell & environment · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small secreted peptides have emerged as key regulators of plant growth, development, and stress adaptation. The Serine-rich endogenous peptide (SCOOP) family represents a unique class of phytocytokines that integrates immune signalling with developmental regulation via the receptor-like kinase MIK2. SCOOP peptides illustrate a significant evolutionary advancement in plants, with lineage-specific signals diversifying to strengthen the relationship between growth and immunity, while their microbial analogues SCOOP-like (SCOOPLs) peptides underscore a cross-kingdom signalling interaction perceived by the flexible MIK2 receptor. This review synthesises current knowledge on the SCOOP-MIK2 signalling module, covering PROSCOOP precursor processing by subtilases, ligand-receptor interactions, and downstream pathways including reactive oxygen species (ROS), MAP kinase cascades, and phytohormone networks. Recent findings reveal that different SCOOP peptides may generate different responses through the same receptor, as shown by SCOOP10 and SCOOP12 in leaf senescence, while SCOOP12 additionally regulates root growth via the MIK2-MPK6-PLETHORA-PIN pathway. These findings underscore the SCOOP-MIK2 axis as a central integrator of growth, defence, and environmental response. Understanding the molecular foundation of SCOOP proteolytic activation, ligand specificity, and interspecies functionality may facilitate the strategic tuning of this pathway, opening novel opportunities for developing stress-resilient plants in response to climate change.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.