Evidence map›Paper›PMID 42186614›Full record

ArticleCureus2026

Diffuse Alveolar Hemorrhage Mimicking Pneumonia in a Patient With Interstitial Lung Disease on Ticagrelor.

Muhammad Usman Shahbaz, Maliha Khalid, Muhammad Usman, Muhammad Zawar Asif, Daphne Macbruce

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad Usman ShahbazInternal Medicine, Mercy Hospital Fort Smith, Fort Smith, USA.
Maliha KhalidInternal Medicine, Jinnah Sindh Medical University, Karachi, PAK.
Muhammad UsmanInternal Medicine, Mercy Hospital Fort Smith, Fort Smith, USA.
Muhammad Zawar AsifInternal Medicine, Mercy Hospital Fort Smith, Fort Smith, USA.
Daphne MacbrucePulmonology and Critical Care, Mercy Hospital Fort Smith, Fort Smith, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse alveolar hemorrhage (DAH) is a rare and potentially life-threatening cause of acute hypoxemic respiratory failure and may be difficult to diagnose in patients with underlying interstitial lung disease (ILD). Ticagrelor frequently causes dyspnea, but DAH related to its use is exceedingly uncommon. We report the case of a 74-year-old man with chronic ILD and recent percutaneous coronary intervention who presented with progressive dyspnea, hypoxemia, and diffuse bilateral ground-glass opacities while receiving dual antiplatelet therapy with ticagrelor. Initial evaluation favored infection or ILD progression. Bronchoscopy with bronchoalveolar lavage demonstrated progressively bloody aliquots, establishing the diagnosis of DAH. Infectious, autoimmune, and thromboembolic causes were excluded, and the temporal relationship to ticagrelor supported a drug-induced etiology. This case highlights the diagnostic challenge of DAH in ILD patients and emphasizes the need for early consideration of medication-related hemorrhage in patients receiving ticagrelor who develop unexplained hypoxemia or hemoptysis.

Indexed as

acute hypoxic respiratory failureaspirin and ticagrelor (dapt)diffuse alveolar hemorrhagediffuse interstitial lung diseasedrug-related side effects and adverse reactions

Identifiers

PMID42186614
PMCPMC13198875

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.