Evidence map›Paper›PMID 42186536›Full record

ArticleBioinformation2024

Insights from the molecular docking and simulation analysis of seocalcitol with ACE2 and vitamin D receptor.

Sumanpreet Kaur, Deepak Yadav, Sukhpreet Singh, Monu Kumari, Deepak Kumar, Kirtimaan Syal, Rajasri Bhattacharyya, Dibyajyoti Banerjee

Abstract read
In one paragraph

Article in Bioinformation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sumanpreet KaurDepartment of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh- 160012, India.
Deepak YadavDepartment of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh- 160012, India.
Sukhpreet SinghDepartment of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh- 160012, India.
Monu KumariDepartment of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh- 160012, India.
Deepak KumarDepartment of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh- 160012, India.
Kirtimaan SyalDepartment of Biological Sciences, Birla Institute of Technology and Science-Pilani, Hyderabad campus, Hyderabad, Telangana -500078, India.
Rajasri BhattacharyyaDepartment of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh- 160012, India.
Dibyajyoti BanerjeeDepartment of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh- 160012, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 has caused a severe impact on global health. Several studies have reported the use of Vitamin D in the management of COVID-19 illness; however, the molecular basis of its action is not clear. This draws an interest to understand the molecular insights of binding of vitamin D and its analogues with ACE2 (angiotensin-converting enzyme 2) and VDR (vitamin D receptor) using molecular docking analysis. Here, we have documented the molecular docking and simulation analysis of the binding interactions of seocalcitol with ACE2 and VDR for further consideration in managing COVID-19.

Indexed as

Angiotensin converting enzyme 2 (ACE2)COVID-19molecular dockingSeocalcitolVitamin Dvitamin D receptor (VDR)

Identifiers

PMID42186536
PMCPMC13198446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.